da Silva Alex Rocha Bernardes, Martinez Laura Christina, de Medeiros Pinheiro Marcelo, Szejnfeld Vera Lúcia
Rheumatology Division, Federal University of Sao Paulo/Paulista School of Medicine (Unifesp/EPM), São Paulo, Brazil.
Arch Osteoporos. 2022 Mar 18;17(1):50. doi: 10.1007/s11657-022-01092-y.
This was a retrospective observational study to determine the secular trends in osteoporosis hip fractures in Brazil from 2004 to 2013. The fracture rates were stable for both sexes, and there was not a secular trend. Fractures were predominant in the South and Southeast Regions. The hip fracture rate was lower in this study than in other studies. These regional differences may be considered in the FRAX Brazil calibration.
Hip fractures are well-known osteoporotic fractures with high mortality and morbidity. Epidemiological studies in Brazil on hip fractures are scarce, and the great majority have been performed in small populations from a few cities. None of these studies has analyzed the long-term hip fracture secular trends, which are important data for the promotion of public health actions.
This was a retrospective observational study with a secular trend analysis in patients over 50 years old who were admitted to the Brazilian Public Health System from 2004 to 2013. We collected hospitalization data according to the ICD-10 for low-trauma hip fractures. The fracture rate was calculated when the patients were stratified by sex, age, and geographic region, and linear regression analysis was performed to evaluate the secular trends.
The hip fracture rate per 100,000 inhabitants was 59.69; the rate was 74.72 in females and 42.95 in males. The fracture rates were higher in the South and Southeast Regions and steadily increased with age, and the average ratio of women-to-men was 1.74. No secular trend was detected in the overall population. Surprisingly, the secular trend only increased in the South region from 2004 to 2013, and the secular trends were stable in the other regions.
Although the secular trend was similar to some worldwide studies, the hip fracture rate was lower than that previously observed in regional studies in Brazil. These regional differences may be considered in the FRAX Brazil calibration.
这是一项回顾性观察研究，旨在确定2004年至2013年巴西骨质疏松性髋部骨折的长期趋势。男女骨折率均保持稳定，不存在长期趋势。骨折在南部和东南部地区最为常见。本研究中的髋部骨折率低于其他研究。在巴西FRAX校准中可考虑这些地区差异。
髋部骨折是众所周知的骨质疏松性骨折，具有较高的死亡率和发病率。巴西关于髋部骨折的流行病学研究较少，绝大多数研究是在少数几个城市的小群体中进行的。这些研究均未分析髋部骨折的长期趋势，而这是促进公共卫生行动的重要数据。
这是一项回顾性观察研究，对2004年至2013年入住巴西公共卫生系统的50岁以上患者进行长期趋势分析。我们根据国际疾病分类第10版收集了低创伤性髋部骨折的住院数据。当患者按性别、年龄和地理区域分层时计算骨折率，并进行线性回归分析以评估长期趋势。
每10万居民中的髋部骨折率为59.69；女性为74.72，男性为42.95。南部和东南部地区的骨折率较高，且随年龄稳步上升，女性与男性的平均比例为1.74。总体人群中未检测到长期趋势。令人惊讶的是，2004年至2013年期间长期趋势仅在南部地区有所上升，其他地区的长期趋势保持稳定。
尽管长期趋势与一些全球研究相似，但巴西的髋部骨折率低于此前在巴西区域研究中观察到的水平。在巴西FRAX校准中可考虑这些地区差异。
