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母亲对自闭症谱系障碍(ASD)病因的看法:随时间的差异以及家庭中ASD经历的影响

Mothers' Ideas About Causes of Autism Spectrum Disorder (ASD): Differences Over Time and by Household Experience with ASD.

作者信息

Bradley Chyrise B, Ashner Marissa C, Kepner Marti W, Garcia Tanya P, Grosser Kyle F, Hightshoe Kristina, Moody Eric J, Reyes Nuri, Rosenberg Steven A, Tapia Amanda L, Daniels Julie L

机构信息

Department of Epidemiology, Gillings School of Global Public Health, The University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.

Department of Biostatistics, Gillings School of Global Public Health, The University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.

出版信息

J Autism Dev Disord. 2025 May 22. doi: 10.1007/s10803-025-06862-4.

Abstract

To understand trends in mothers' causal ideas about autism spectrum disorder (ASD) that may be important in targeting education efforts for parents and healthcare providers, as these may be associated with healthcare choices. Data from the Study to Explore Early Development (SEED) was used to examine the causal ideas mothers had, sociodemographic characteristics associated with causal ideas, and whether reported ideas differed over time. SEED included 8307 mothers of pre-school children, with and without ASD, who completed a maternal phone interview between 2007 and 2020. Less than half of mothers (39.3%) offered a causal idea. The most frequently offered causal ideas were genetics, vaccines, environment, parent lifestyle issues, pre/peri-pregnancy maternal medical issues, labor/delivery experiences, and child diet. Some aspects of sociodemographic characteristics, particularly ethno-cultural background, were significantly associated with reporting several causal ideas. Odds of reporting vaccines decreased over time while odds of reporting genetics, parent lifestyle, maternal medical, or labor/delivery issues increased over time. There were significant differences in odds of reporting several causal ideas between those with and those without a child with ASD in the household. Causal ideas reported were consistent with prior research but important differences between those with and those without household ASD as well as significant time trends for certain causes were noted. Implications for public health communication and future research are discussed.

摘要

为了解母亲们关于自闭症谱系障碍(ASD)的因果观念趋势,这对于针对家长和医疗服务提供者的教育工作可能很重要,因为这些观念可能与医疗选择相关。探索早期发育研究(SEED)的数据被用于研究母亲们的因果观念、与因果观念相关的社会人口学特征,以及所报告的观念是否随时间而变化。SEED包括8307名学龄前儿童的母亲,这些儿童有的患有ASD,有的没有,她们在2007年至2020年期间完成了一次母亲电话访谈。不到一半的母亲(39.3%)提出了因果观念。最常被提及的因果观念是基因、疫苗、环境、父母生活方式问题、孕前/孕期母亲医疗问题、分娩经历和儿童饮食。社会人口学特征的某些方面,特别是种族文化背景,与报告多种因果观念显著相关。随着时间的推移,报告疫苗是病因的几率下降,而报告基因、父母生活方式、母亲医疗或分娩问题是病因的几率上升。家中有患ASD孩子的母亲和没有患ASD孩子的母亲在报告多种因果观念的几率上存在显著差异。所报告的因果观念与先前的研究一致,但注意到家中有ASD孩子和没有ASD孩子的母亲之间存在重要差异,以及某些病因存在显著的时间趋势。文中讨论了对公共卫生宣传和未来研究的启示。

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