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单卵双胞胎中的哮喘和变应性曲霉菌病

Asthma and allergic aspergillosis in monozygotic twins.

作者信息

Starke I D

出版信息

Br J Dis Chest. 1985 Jul;79(3):295-300.

PMID:4040385
Abstract

Monozygotic twins are reported; both had bronchial asthma with type I hypersensitivity to Aspergillus fumigatus but only one had type III hypersensitivity, together with pulmonary infiltrations compatible with the diagnosis of allergic bronchopulmonary aspergillosis. It is suggested that non-inherited factors other than the intensity of exposure to antigen may be important in determining the development of allergic bronchopulmonary aspergillosis.

摘要

有单卵双胞胎的报道;两人均患有支气管哮喘,对烟曲霉有I型超敏反应,但只有一人有III型超敏反应,同时伴有与变应性支气管肺曲霉病诊断相符的肺部浸润。有人提出,除了抗原暴露强度之外的非遗传因素在变应性支气管肺曲霉病的发生发展中可能很重要。

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