Salem P A, Habboubi N, Anaissie E, Brihi E R, Issa P, Abbas J S, Khalyl M F
Cancer Treat Rep. 1985 Jul-Aug;69(7-8):891-3.
The therapeutic activity of cisplatin was explored in three consecutive patients with locoregional squamous cell carcinoma of the anus who received no prior therapy. One complete response and two partial responses were achieved. These data, although preliminary, strongly suggest that this disease is sensitive to cisplatin, and further trials are indicated to assess the precise role of this drug in the overall management of anal carcinoma.
对3例未经前期治疗的局部区域型肛管鳞状细胞癌患者连续进行了顺铂治疗活性的研究。获得了1例完全缓解和2例部分缓解。这些数据尽管是初步的,但强烈提示该疾病对顺铂敏感,因此有必要进行进一步试验以评估该药在肛管癌整体治疗中的确切作用。