实验性移植物抗宿主病中胆管上皮细胞上MHC II类抗原的表达
Expression of MHC class II antigens on bile duct epithelium in experimental graft versus host disease.
作者信息
Takács L, Szende B, Rot A, Diamanstein T
出版信息
Clin Exp Immunol. 1985 Jun;60(3):449-56.
Abstract
Recently we observed the expression of MHC class II antigens on bile duct epithelium in human liver transplantation rejection. In this report we present evidence for the expression of MHC class II antigens on bile duct epithelium in experimental GVHD. These findings support the idea, that the target tissue elements in liver transplantation rejection and GVHD are the bile ducts, on the other hand this is a new experimental model for the analysis of MHC class II antigen expression on epithelial tissue.
摘要
最近我们观察到在人类肝移植排斥反应中，胆管上皮细胞上有MHC II类抗原的表达。在本报告中，我们提供了在实验性移植物抗宿主病（GVHD）中胆管上皮细胞上表达MHC II类抗原的证据。这些发现支持了这样一种观点，即肝移植排斥反应和GVHD中的靶组织成分是胆管，另一方面，这是分析上皮组织上MHC II类抗原表达的一种新的实验模型。
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