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翼腭窝孤立性纤维瘤:1例罕见病例报告及文献复习

Solitary fibrous tumor in the pterygopalatine fossa: a rare case report and literature review.

作者信息

Zhou Jian-Sheng, Yuan Hui, Chen Jiu-Qiang, Shen Lei

机构信息

Department of Otolaryngology, Second Affiliated Hospital, Zhejiang University School of Medicine, 88 Jie-fang Road, Hangzhou, 310009, Zhejiang Province, China.

Department of Otolaryngology, Qingtian County People's Hospital, Qingtian, China.

出版信息

Eur Arch Otorhinolaryngol. 2025 May 22. doi: 10.1007/s00405-025-09440-7.

Abstract

INTRODUCTION

Solitary fibrous tumor is a rare spindle cell tumor that may occur in various parts of the body. No documented case of solitary fibrous tumor has been reported in pterygopalatine fossa.

CASE REPORT

A 25-year-old male complained of right facial numbness for 20 days. Computed tomography of the paranasal sinuses demonstrated a well-circumscribed lesion centered in the right pterygopalatine fossa. On magnetic resonance imaging the lesion was homogenously isointense to muscle on T1 weighted imaging (T1WI) and slightly hyperintense to muscle on T2 weighted (T2WI). The intro-operative frozen pathology reveals a benign spindle cell tumor. The tumor was removed successfully via transnasal combined with Caldwell-Luc approach without complications. However, the final pathology combined with immunohistochemistry confirmed the diagnosis of solitary fibrous tumor. No further radiotherapy is performed post-operation. After half a year follow up, there is no recurrence.

CONCLUSION

For the tumor in the pterygopalatine fossa, the possibility of solitary fibrous tumor should be considered and radical endoscopic resection should be the preferred treatment approach.

摘要

引言

孤立性纤维瘤是一种罕见的梭形细胞肿瘤,可发生于身体的各个部位。翼腭窝尚未有孤立性纤维瘤的病例报道。

病例报告

一名25岁男性,主诉右侧面部麻木20天。鼻窦计算机断层扫描显示,一个边界清晰的病变位于右侧翼腭窝。在磁共振成像中,该病变在T1加权成像(T1WI)上与肌肉呈等信号,在T2加权成像(T2WI)上略高于肌肉信号。术中冰冻病理显示为良性梭形细胞肿瘤。通过经鼻联合柯-陆氏进路成功切除肿瘤,无并发症。然而,最终病理结合免疫组化确诊为孤立性纤维瘤。术后未进行进一步放疗。随访半年,无复发。

结论

对于翼腭窝肿瘤,应考虑孤立性纤维瘤的可能性,根治性内镜切除应作为首选治疗方法。

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