让一百多名患者冒着手臂淋巴水肿的风险去使一名患者受益——这值得吗？ - Suppr

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超能文献

Risking arm lymphedema in more than a hundred patients to benefit one patient-is it worth it?

作者信息

Lim Geok Hoon, Yap Yoon-Sim, Lim Rui Jun, Leong Lester Chee Hao

机构信息

Breast Department, KK Women's and Children's Hospital, Singapore, Singapore.

Duke-NUS Medical School, Singapore, Singapore.

出版信息

Gland Surg. 2025 Apr 30;14(4):781-784. doi: 10.21037/gs-2025-34. Epub 2025 Apr 25.

DOI:10.21037/gs-2025-34

PMID:40405964

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12093178/

Abstract

摘要

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Risking arm lymphedema in more than a hundred patients to benefit one patient-is it worth it?让一百多名患者冒着手臂淋巴水肿的风险去使一名患者受益——这值得吗？

Gland Surg. 2025 Apr 30;14(4):781-784. doi: 10.21037/gs-2025-34. Epub 2025 Apr 25.

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Using the axillary reverse mapping technique to screen breast cancer patients with a high risk of lymphedema.采用腋窝反向绘图技术筛查患淋巴水肿风险较高的乳腺癌患者。

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Upper outer boundaries of the axillary dissection. Result of the SENTIBRAS protocol: Multicentric protocol using axillary reverse mapping in breast cancer patients requiring axillary dissection.腋窝清扫的上外侧边界。SENTIBRAS方案的结果：在需要腋窝清扫的乳腺癌患者中使用腋窝反向映射的多中心方案。

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Does Axillary Reverse Mapping Prevent Lymphedema After Lymphadenectomy?腋窝反向映射能否预防淋巴结清扫术后的淋巴水肿？

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The Efficacy of Axillary Reverse Mapping for the Prevention of Lymphedema.腋窝反向绘图预防淋巴水肿的疗效。

Am Surg. 2024 Feb;90(2):199-206. doi: 10.1177/00031348231198103. Epub 2023 Aug 24.

Clinical application of axillary reverse mapping in patients with breast cancer: A systematic review and meta-analysis.腋窝反向绘图在乳腺癌患者中的临床应用：系统评价和荟萃分析。

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Sentinel lymph node biopsy lowers the rate of lymphedema when compared with standard axillary lymph node dissection.与标准腋窝淋巴结清扫术相比，前哨淋巴结活检降低了淋巴水肿的发生率。

Am Surg. 2003 Mar;69(3):209-11; discussion 212.

本文引用的文献

A phase III trial of adjuvant ribociclib plus endocrine therapy versus endocrine therapy alone in patients with HR-positive/HER2-negative early breast cancer: final invasive disease-free survival results from the NATALEE trial.一项针对激素受体阳性/人表皮生长因子受体2阴性早期乳腺癌患者的辅助性瑞博西尼联合内分泌治疗与单纯内分泌治疗的III期试验：NATALEE试验的最终无侵袭性疾病生存期结果

Ann Oncol. 2025 Feb;36(2):149-157. doi: 10.1016/j.annonc.2024.10.015. Epub 2024 Oct 21.

Cost-effectiveness of CDK4/6 inhibitors in HR+/HER2- metastatic breast cancer: a systematic review and meta-analysis.CDK4/6抑制剂在激素受体阳性/人表皮生长因子受体2阴性转移性乳腺癌中的成本效益：一项系统评价和荟萃分析。

Curr Med Res Opin. 2024 Oct;40(10):1753-1767. doi: 10.1080/03007995.2024.2402074. Epub 2024 Sep 21.

Abemaciclib Therapy Using the MonarchE Criteria Results in Large Numbers of Excess Axillary Node Clearances-Time to Pause and Reflect?使用MonarchE标准的阿贝西利治疗导致大量额外的腋窝淋巴结清扫——是时候暂停并反思了？

Cancers (Basel). 2024 Sep 4;16(17):3072. doi: 10.3390/cancers16173072.

Completion axillary lymph node dissection for the identification of pN2-3 status as an indication for adjuvant CDK4/6 inhibitor treatment: a post-hoc analysis of the randomised, phase 3 SENOMAC trial.完成腋窝淋巴结清扫术以确定 pN2-3 状态作为辅助 CDK4/6 抑制剂治疗的指征：随机、III 期 SENOMAC 试验的事后分析。

Lancet Oncol. 2024 Sep;25(9):1222-1230. doi: 10.1016/S1470-2045(24)00350-4. Epub 2024 Aug 6.

Time to abandon axillary lymph node dissection in early-stage breast cancer.是时候摒弃早期乳腺癌的腋窝淋巴结清扫术了。

Lancet Oncol. 2024 Sep;25(9):1111-1113. doi: 10.1016/S1470-2045(24)00385-1. Epub 2024 Aug 6.

Ribociclib plus Endocrine Therapy in Early Breast Cancer.来曲唑联合内分泌治疗早期乳腺癌。

N Engl J Med. 2024 Mar 21;390(12):1080-1091. doi: 10.1056/NEJMoa2305488.

Use of axillary ultrasound to guide breast cancer management in the genomic assay era.在基因组检测时代，使用腋窝超声引导乳腺癌管理。

Breast Dis. 2024;43(1):19-23. doi: 10.3233/BD-230032.

Surgical treatment of breast cancer related lymphedema-the combined approach: a literature review.乳腺癌相关淋巴水肿的外科治疗——联合治疗方法：文献综述

Gland Surg. 2023 Dec 26;12(12):1746-1759. doi: 10.21037/gs-23-247. Epub 2023 Dec 22.

Adjuvant Abemaciclib Plus Endocrine Therapy for Hormone Receptor-Positive, Human Epidermal Growth Factor Receptor 2-Negative, High-Risk Early Breast Cancer: Results From a Preplanned monarchE Overall Survival Interim Analysis, Including 5-Year Efficacy Outcomes.辅助阿贝西利联合内分泌治疗激素受体阳性、人表皮生长因子受体 2 阴性、高危早期乳腺癌： monarchE 总生存期中期分析的预先计划结果，包括 5 年疗效结果。

J Clin Oncol. 2024 Mar 20;42(9):987-993. doi: 10.1200/JCO.23.01994. Epub 2024 Jan 9.

Should patients with hormone receptor-positive, HER2-negative breast cancer and one or two positive sentinel nodes undergo axillary dissection to determine candidacy for adjuvant abemaciclib?对于激素受体阳性、HER2 阴性乳腺癌且有一个或两个前哨淋巴结阳性的患者，是否应行腋窝清扫术以确定辅助阿贝西利治疗的适应证？

Cancer. 2024 Apr 1;130(7):1052-1060. doi: 10.1002/cncr.35136. Epub 2023 Nov 29.

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