Roberto Queiroz Paulo, Dos Santos Marquiony Marques, Lopes Ana Karla Bezerra, da Silva Jose Adailton, Aranha Filho Brunno Giordano da Silva, Costa Thalia Giesta, Bezerra André Carlos Nogueira, Lima Kenio Costa
Departamento de Ciências da Saúde, Programa de Pós-graduação em Ciências da Saúde, Universidade Federal do Rio Grande do Norte, Natal, Brazil.
Departamento de Enfermagem, Universidade do Estado do Rio Grande do Norte, Caicó, Brazil.
Front Public Health. 2025 May 8;13:1465799. doi: 10.3389/fpubh.2025.1465799. eCollection 2025.
This study aimed to analyze the prevalence of syphilis and assess the factors associated with its diagnosis throughout life.
Cross-sectional study conducted from January to April 2022 with 812 MSM users of dating apps in Brazil. Sociodemographic, behavioral, and sexual aspects, health issues, and the use of dating apps variables were analyzed.
Multivariate logistic regression estimated the predictors of syphilis at a 95% confidence interval. The prevalence of syphilis diagnoses was 34.23% (95% CI = 30.94-37.46), and the factors associated with the diagnosis throughout life were age ≥ 30 years (adjusted prevalence ratio [aPR] = 1.49; adjusted 95% confidence interval [a95%CI] = 1.15-1.92), more than three sexual relations with Cis men (aPR = 1.40; a95%CI = 1.03-1.90), sex simultaneously with two people or more during social distancing (aPR = 1.31; a95%CI = 1.00-1.73), use of a licit (or illicit) substance in the last 3 months (aPR = 1.35; a95%CI = 1.05-1.74), using condom less than half of the time in anal sex in the last 3 months (aPR = 1.42, a95%CI = 1.07-1.89), being a PrEP user (aPR = 1.10; a95%CI = 0.81-1.51) and having used the Grindr® app in the last 3 months (aPR = 1.38; a95%CI = 1.04-1.83).
The prevalence of syphilis among MSM users of dating apps is at worrying levels. Thus, frequent testing (less than 3 months for MSM using PrEP and semi-annual for everyone, regardless of the risk), access to DoxiPEP for this population, consistent use of condoms, and the use of apps as a strategic intervention and educommunication platforms are essential to prevent the spread of syphilis.
本研究旨在分析梅毒的患病率，并评估一生中与梅毒诊断相关的因素。
2022年1月至4月对巴西812名使用约会应用程序的男男性行为者进行横断面研究。分析了社会人口统计学、行为和性方面、健康问题以及约会应用程序变量的使用情况。
多变量逻辑回归在95%置信区间估计梅毒的预测因素。梅毒诊断的患病率为34.23%（95%CI = 30.94 - 37.46），与一生诊断相关的因素包括年龄≥30岁（调整患病率比[aPR]=1.49；调整95%置信区间[a95%CI]=1.15 - 1.92）、与顺性别男性发生三次以上性关系（aPR = 1.40；a95%CI = 1.03 - 1.90）、在社交距离期间与两人或更多人同时发生性行为（aPR = 1.31；a95%CI = 1.00 - 1.73）、在过去3个月内使用合法（或非法）物质（aPR = 1.35；a95%CI = 1.05 - 1.74）、在过去3个月内肛交时使用避孕套的时间少于一半（aPR = 1.42，a95%CI = 1.07 - 1.89）、是暴露前预防（PrEP）使用者（aPR = 1.10；a95%CI = 0.81 - 1.51）以及在过去3个月内使用过Grindr®应用程序（aPR = 1.38；a95%CI = 1.04 - 1.83）。
约会应用程序的男男性行为者用户中梅毒患病率处于令人担忧的水平。因此，频繁检测（使用PrEP的男男性行为者检测间隔少于3个月，所有人无论风险高低均每半年检测一次）、为该人群提供多西环素预防暴露后感染（DoxiPEP）、持续使用避孕套以及将应用程序用作战略干预和教育传播平台对于预防梅毒传播至关重要。
