顺铂、阿霉素和甲氨蝶呤治疗复发性宫颈癌。
Cis-platinum, doxorubicin, and methotrexate treatment for recurrent cervical cancer.
作者信息
Wheelock J B, Krebs H B, Goplerud D R, Myers M
出版信息
Obstet Gynecol. 1985 Sep;66(3):410-2.
PMID:4040622
Abstract
A combination of cis-platinum, doxorubicin (Adriamycin), and methotrexate was used to treat 28 patients with recurrent cervical cancer. Seven patients achieved a partial response with a median duration of ten months. Two patients achieved a complete response with a median duration of 14 months. The overall response rate was 32%. Ten patients with stable disease had a median progression-free interval of 4.5 months. Toxicity was acceptable.
摘要
顺铂、阿霉素（多柔比星）和甲氨蝶呤联合用药治疗28例复发性宫颈癌患者。7例患者部分缓解，中位缓解持续时间为10个月。2例患者完全缓解，中位缓解持续时间为14个月。总缓解率为32%。10例病情稳定的患者中位无进展生存期为4.5个月。毒性反应可接受。
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