Cunha Carolina Maria Pires, Amorim Melania Maria Ramos, Guendler Julianna de Azevedo, Souza Alex Sandro Rolland, Katz Leila
Instituto de Medicina Integral Prof. Fernando Figueira RecifePE Brazil Instituto de Medicina Integral Prof. Fernando Figueira, Recife, PE, Brazil.
Universidade Federal de Campina Grande Campina GrandePB Brazil Universidade Federal de Campina Grande, Campina Grande, PB, Brazil.
Rev Bras Ginecol Obstet. 2025 Apr 30;47. doi: 10.61622/rbgo/2025rbgo14. eCollection 2025.
This study described the clinical and epidemiological profile and the management provided to pregnant and postpartum women with COVID-19 who required respiratory support.
A descriptive study was conducted with pregnant and postpartum women with confirmed COVID-19 who received care between April 2020 and December 2021 in eight referral centers in northeastern Brazil. Statistical analysis was conducted using Epi-Info 7.2.5 and Medcalc, version 20.112.
Of the 720 patients admitted, 208 (32.7%) required respiratory support. Mean age of the participants was 28.9±7.1 years. Most (52.8%) were brown-skinned; 31.3% had little formal schooling; 41.1% had a personal income and 23.1% were married. Around half were referred from another hospital. Overall, 36.8% were obese and 36.9% were hypertensive. Criteria for severe acute respiratory syndrome (SARS) were present in 80.7% of cases. Overall, 151 patients (74.7%) required corticoids, and 150 (76.1%) were admitted to an intensive care unit. Non-invasive ventilation was needed in 89.4% of cases, with nasal catheters being the most common type (55.3% of cases). Invasive mechanical ventilation was necessary in 35.5% of cases and 91.6% had a cesarean section. Maternal near miss and death occurred in 24% and 12.9% of cases, respectively.
Pregnant and postpartum women with COVID-19 who required respiratory support were predominantly brown-skinned, in the third trimester of pregnancy and had been referred from another hospital. The cesarean section rate was high; the presence of criteria for SARS was common and the rates of COVID-19-related maternal near miss and death were high.
NCT04462367.
本研究描述了需要呼吸支持的新冠肺炎孕妇和产后妇女的临床和流行病学特征以及所接受的治疗。
对2020年4月至2021年12月期间在巴西东北部8个转诊中心接受治疗的确诊新冠肺炎孕妇和产后妇女进行了描述性研究。使用Epi-Info 7.2.5和Medcalc 20.112版进行统计分析。
在720名入院患者中，208名（32.7%）需要呼吸支持。参与者的平均年龄为28.9±7.1岁。大多数（52.8%）为棕色皮肤；31.3%受教育程度低；41.1%有个人收入，23.1%已婚。约一半是从另一家医院转诊而来。总体而言，36.8%肥胖，36.9%患有高血压。80.7%的病例存在严重急性呼吸综合征（SARS）标准。总体而言，151名患者（74.7%）需要使用皮质类固醇，150名（76.1%）被收入重症监护病房。89.4%的病例需要无创通气，鼻导管是最常见的类型（55.3%的病例）。35.5%的病例需要有创机械通气，91.6%进行了剖宫产。孕产妇险些死亡和死亡分别发生在24%和12.9%的病例中。
需要呼吸支持的新冠肺炎孕妇和产后妇女主要为棕色皮肤，处于妊娠晚期，且是从另一家医院转诊而来。剖宫产率高；SARS标准常见，与新冠肺炎相关的孕产妇险些死亡和死亡率高。
NCT04462367。
