Van Grambezen Aurianne, Steenhaut Patricia, Van Grambezen Bénédicte, Debiève Frédéric, Bernard Pierre, Hubinont Corinne
Department of Obstetrics, Saint Luc University Hospital, Brussels B-1200, Belgium.
Department of Neonatology, Saint Luc University Hospital, Brussels B-1200, Belgium.
Matern Fetal Med. 2022 Sep 27;4(4):276-285. doi: 10.1097/FM9.0000000000000173. eCollection 2022 Oct.
The rate of twin pregnancies has increased over the last decades, largely because of the ongoing development of assisted reproductive technology and increased maternal age at childbearing. Twins have a higher risk of adverse outcomes during pregnancy and the perinatal period. The prevalence of umbilical cord abnormalities is higher for twin pregnancies compared with singleton pregnancies. Some of these abnormalities are nonspecific to twinning and can also be found in singleton gestations (such as velamentous cord insertion, vasa previa, and single umbilical artery). Other abnormalities are associated with monochorionic twins, such as umbilical cord entanglement, and umbilical proximate cord insertion. Most of these abnormalities can be detected by ultrasound evaluation. The early and accurate ultrasound diagnosis of chorionicity, amnionicity, and placental and umbilical cord characteristics is crucial if we are to predict the risk of complications and to determine the best management for twin pregnancies. Histopathological examination of the placenta and umbilical cord after delivery can help to confirm prenatal diagnosis and to provide a better understanding of the physiopathology of their abnormalities. The aim of this review was to emphasize the role that the umbilical cord plays in twin complications and to describe the management of these high-risk pregnancies.
在过去几十年中,双胎妊娠的发生率有所上升,这主要归因于辅助生殖技术的不断发展以及孕产妇生育年龄的增加。双胎在孕期和围产期出现不良结局的风险更高。与单胎妊娠相比,双胎妊娠中脐带异常的发生率更高。其中一些异常并非双胎特有,在单胎妊娠中也可发现(如帆状脐带附着、前置血管和单脐动脉)。其他异常则与单绒毛膜双胎有关,如脐带缠绕和脐带近脐部附着。这些异常大多可通过超声检查发现。如果我们要预测并发症风险并确定双胎妊娠的最佳管理方案,早期准确的超声诊断绒毛膜性、羊膜性以及胎盘和脐带特征至关重要。分娩后对胎盘和脐带进行组织病理学检查有助于证实产前诊断,并更好地理解其异常的病理生理学。本综述的目的是强调脐带在双胎并发症中的作用,并描述这些高危妊娠的管理方法。