Jolaoye Oladoyin Ogunbayo
Internal Medicine - Pediatrics, Order of Saint Francis Medical Center, University of Illinois College of Medicine at Peoria, Peoria, USA.
Cureus. 2025 Apr 22;17(4):e82806. doi: 10.7759/cureus.82806. eCollection 2025 Apr.
Brachioradial pruritus (BRP) is a type of localized neuropathic dysesthesia of the dorsolateral upper extremities that is commonly found in fair-skinned females. It is worsened by exposure to bright sunlight or ultraviolet radiation (UVR), a subtype of neuropathic pruritus that is delayed and difficult to diagnose. It typically involves a combination of C5-C6 dermatomal distribution of the dorsolateral arm (often bilateral), spinal abnormality, and radiculopathy. The ice-pack sign is universally known to be associated with BRP. We present a case of a 41-year-old Caucasian female who presented with complaints of sunburn to bilateral arms, pins and needles, and extreme itching sensation in the bilateral upper arms. The patient tried lotions, cortisone cream, and oral Benadryl without relief. The patient reported that the rash worsened with heat and improved with ice packs. On the primary survey, vitals were stable, but the presence of dark erythema on the bilateral upper arms was visible. The patient was recommended to apply silver sulfadiazine 1% cream twice daily, oral gabapentin 300 mg twice daily, and topical diclofenac gel as needed. The patient saw a primary care physician (PCP), dermatology, and neurology, with broad differential diagnoses, and underwent several treatments for other diseases, but the primary diagnosis of BRP was not established. Early recognition and diagnosis of BRP, by taking a thorough history and physical exam, and utilization of the ice-pack test, is critical for prompt management and avoiding unnecessary workup.
臂桡侧瘙痒症(BRP)是一种常见于皮肤白皙女性的上肢背外侧局部性神经病理性感觉异常。暴露于强光或紫外线辐射(UVR)会使其加重,它是一种延迟且难以诊断的神经病理性瘙痒症亚型。它通常涉及臂背外侧C5 - C6皮节分布(常为双侧)、脊柱异常和神经根病的组合。冰敷征与BRP普遍相关。我们报告一例41岁的白种女性患者,她主诉双侧手臂晒伤、有针刺感以及双侧上臂极度瘙痒。患者尝试使用洗剂、可的松乳膏和口服苯海拉明,但均无缓解。患者报告皮疹遇热加重,冰敷后改善。在初步检查中,生命体征稳定,但双侧上臂可见暗红色红斑。建议患者每天两次涂抹1%磺胺嘧啶银乳膏,每天两次口服加巴喷丁300毫克,并根据需要使用双氯芬酸凝胶。患者就诊于初级保健医生(PCP)、皮肤科和神经科,鉴别诊断范围广泛,并接受了针对其他疾病的多种治疗,但未确诊为BRP。通过全面的病史采集和体格检查以及使用冰敷试验对BRP进行早期识别和诊断,对于及时管理和避免不必要的检查至关重要。