Abdurabu Mohammed, Salem Waleed
Emergency Medicine, Hamad Medical Corporation, Doha, QAT.
Emergency Medicine, Hamad General Hospital, Doha, QAT.
Cureus. 2025 Apr 21;17(4):e82748. doi: 10.7759/cureus.82748. eCollection 2025 Apr.
Insecticides have great efficacy and are used in homes and agricultural fields across the globe, including pyrethrins and their synthetic equivalents, or pyrethroids. Among their compounds are deltamethrin and imiprothrin, which are present in many insecticide sprays. Humans can become toxically exposed to them through ingestion, skin contact, or inadvertent inhalation. In humans, gastrointestinal and neurotoxic side effects are frequently observed in cases of acute oral intoxication. Although they have not been well documented up to this point, pyrethroids have occasionally caused cardiotoxic consequences after consumption. This case describes a deliberate instance of pyrethroid ingestion that resulted in acute symptoms such as persistent tachycardia and a reduction in the level of consciousness. The patient underwent intensive care follow-up with a favorable outcome. Comparing our case with the available literature highlighted how rare cardiac involvement is in pyrethroid toxicity and emphasized the need for further research to verify the exact mechanism of its effects.
杀虫剂功效显著，在全球各地的家庭和农田中都有使用，包括除虫菊酯及其合成类似物，即拟除虫菊酯。其化合物中有溴氰菊酯和炔咪菊酯，存在于许多杀虫剂喷雾中。人类可通过摄入、皮肤接触或意外吸入而受到其毒性影响。在人类中，急性口服中毒时经常会观察到胃肠道和神经毒性副作用。尽管到目前为止尚未有充分记录，但拟除虫菊酯在摄入后偶尔会导致心脏毒性后果。本病例描述了一次故意摄入拟除虫菊酯的情况，导致出现持续心动过速和意识水平下降等急性症状。患者接受了重症监护随访，结果良好。将我们的病例与现有文献进行比较，凸显了拟除虫菊酯毒性中心脏受累情况的罕见性，并强调需要进一步研究以验证其确切作用机制。
