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一名儿科患者的坏血病:现代世界中的罕见诊断。

Scurvy in a Pediatric Patient: A Rare Diagnosis in the Modern World.

作者信息

Pavlidou Evdokia, Georgoulis Athanasios, Zarenti Sofia, Doufexi Aikaterini Elisavet

机构信息

School of Dentistry, Aristotle University of Thessaloniki, Thessaloniki, GRC.

Medical School, Aristotle University of Thessaloniki, Thessaloniki, GRC.

出版信息

Cureus. 2025 Apr 22;17(4):e82766. doi: 10.7759/cureus.82766. eCollection 2025 Apr.

DOI:10.7759/cureus.82766
PMID:40406767
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12096419/
Abstract

Scurvy is the oldest-known nutritional disorder caused by a sustained lack of ascorbic acid (vitamin C). Despite its rarity in developed countries, scurvy has been increasingly reported in recent years in pediatric patients, particularly those with selective or restricted feeding. It mainly affects the musculoskeletal system, the skin, and the oral cavity, causing gingival bleeding. Diagnosing scurvy can be difficult for clinicians because of its nonspecific symptoms, often leading to extensive testing and delayed identification of the condition. The treatment is based on changing eating habits and taking supplements with vitamin C. This study aims to present a case report of a 12-year-old child with oral manifestations of scurvy, discussing the differential diagnosis, clinical findings, and therapeutic approach, while also reviewing current literature on the topic.

摘要

坏血病是已知最古老的由长期缺乏抗坏血酸(维生素C)引起的营养失调症。尽管在发达国家坏血病较为罕见,但近年来在儿科患者中报告的病例越来越多,尤其是那些有选择性或受限饮食的患者。它主要影响肌肉骨骼系统、皮肤和口腔,导致牙龈出血。由于坏血病的症状不具特异性,临床医生诊断起来可能会很困难,这往往导致进行广泛的检查并延迟对病情的识别。治疗方法是改变饮食习惯并补充维生素C。本研究旨在呈现一例12岁患有坏血病口腔表现的儿童病例报告,讨论鉴别诊断、临床发现和治疗方法,同时也回顾关于该主题的当前文献。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/18c5/12096419/e39d57f672dc/cureus-0017-00000082766-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/18c5/12096419/eb7a7b6b36c7/cureus-0017-00000082766-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/18c5/12096419/07273da534df/cureus-0017-00000082766-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/18c5/12096419/43eb09883c77/cureus-0017-00000082766-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/18c5/12096419/e39d57f672dc/cureus-0017-00000082766-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/18c5/12096419/eb7a7b6b36c7/cureus-0017-00000082766-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/18c5/12096419/07273da534df/cureus-0017-00000082766-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/18c5/12096419/43eb09883c77/cureus-0017-00000082766-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/18c5/12096419/e39d57f672dc/cureus-0017-00000082766-i04.jpg

相似文献

1
Scurvy in a Pediatric Patient: A Rare Diagnosis in the Modern World.一名儿科患者的坏血病:现代世界中的罕见诊断。
Cureus. 2025 Apr 22;17(4):e82766. doi: 10.7759/cureus.82766. eCollection 2025 Apr.
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Childhood scurvy: an unusual cause of refusal to walk in a child.儿童坏血病:儿童拒绝行走的罕见原因。
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Scurvy may occur even in children with no underlying risk factors: a case report.即使在没有潜在风险因素的儿童中也可能发生坏血病:一例病例报告。
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Scurvy: still a threat in the well-fed first world?坏血病:营养充足的第一世界仍面临威胁?
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[Eat a citrus fruit, stay healthy--a case report of scurvy].[吃柑橘类水果,保持健康——一例坏血病病例报告]
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The risk for scurvy in children with neurodevelopmental disorders.神经发育障碍儿童患坏血病的风险。
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Difficult to think about but easy to treat: scurvy.难以想象却易于治疗:坏血病。
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本文引用的文献

1
Scurvy in an Adolescent: A Case Report.一名青少年的坏血病:病例报告
Cureus. 2024 Apr 22;16(4):e58782. doi: 10.7759/cureus.58782. eCollection 2024 Apr.
2
Scurvy masquerading as IgA vasculitis.坏血病伪装成 IgA 血管炎。
Pediatr Rheumatol Online J. 2024 May 18;22(1):56. doi: 10.1186/s12969-024-00992-2.
3
A Rare Presentation of Scurvy in a Well-Nourished Patient.营养良好患者的坏血病罕见病例
Cureus. 2023 Oct 2;15(10):e46379. doi: 10.7759/cureus.46379. eCollection 2023 Oct.
4
Scurvy and food selectivity in childhood: a case report.坏血病与儿童时期的食物选择性:一例报告。
Einstein (Sao Paulo). 2023 Sep 8;21:eRC0356. doi: 10.31744/einstein_journal/2023RC0356. eCollection 2023.
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Scurvy in a 29-Month-Old Patient Presenting With a Gower Sign.一名29个月大出现Gower征的坏血病患者
Cureus. 2022 Sep 19;14(9):e29342. doi: 10.7759/cureus.29342. eCollection 2022 Sep.
6
When the limp has a dietary cause: A retrospective study on scurvy in a tertiary Italian pediatric hospital.当跛行由饮食原因引起时:意大利一家三级儿科医院坏血病的回顾性研究。
Front Pediatr. 2022 Sep 14;10:981908. doi: 10.3389/fped.2022.981908. eCollection 2022.
7
Scurvy presenting primarily as gingival manifestation in a young child: a diagnostic dilemma.坏血病主要表现为牙龈表现,发生于一幼儿:诊断难题。
BMJ Case Rep. 2022 Jun 20;15(6):e249113. doi: 10.1136/bcr-2022-249113.
8
Scurvy in Children: The Silent Masquerader.儿童坏血病:沉默的伪装者。
J Trop Pediatr. 2022 Apr 5;68(3). doi: 10.1093/tropej/fmac029.
9
Scurvy in the Modern World: Extinct or Not?现代世界中的坏血病:绝迹了还是依然存在?
Cureus. 2022 Feb 26;14(2):e22622. doi: 10.7759/cureus.22622. eCollection 2022 Feb.
10
A Narrative Review on Pediatric Scurvy: The Last Twenty Years.儿童坏血病:近 20 年的研究进展述评
Nutrients. 2022 Feb 6;14(3):684. doi: 10.3390/nu14030684.