Jadhav Kavita, Venkateswaran Rajalakshmi, Waghmare Rukmini, Bakhshi Girish, Jaiswal Yogesh
General Surgery, Grant Government Medical College and Sir J.J. Group of Hospitals, Mumbai, IND.
Plastic and Reconstructive Surgery, Grant Government Medical College and Sir J.J. Group of Hospitals, Mumbai, IND.
Cureus. 2025 Apr 22;17(4):e82797. doi: 10.7759/cureus.82797. eCollection 2025 Apr.
Trichoblastic carcinoma is a rare skin adnexal malignancy. It often resembles other skin malignancies in its gross and histopathological picture. While the definitive treatment for low-grade lesions is wide local excision, high-grade or inoperable lesions require chemo-radiation. It is important to ensure excision of an adequate clear skin margin while doing a surgical resection. The present case reports a 75-year-old male with a malignant skin lesion on his right clavicle. Magnetic resonance imaging showed it to involve the muscles and clavicle. Preoperative biopsy showed features of a trichilemmal carcinoma. A wide local excision of the part of the clavicle was done. A trapezius flap was mobilized to cover the defect. Histopathology and immunohistochemistry analysis confirmed the diagnosis of a low-grade trichoblastic carcinoma. This case report aims to emphasize that trichoblastic carcinoma can be considered one of the differentials of skin adnexal malignancies, and it needs a multidisciplinary approach to manage such rare malignancies.
毛母质癌是一种罕见的皮肤附属器恶性肿瘤。其大体和组织病理学表现常与其他皮肤恶性肿瘤相似。对于低级别病变， definitive治疗方法是广泛局部切除，而高级别或无法手术切除的病变则需要放化疗。手术切除时确保切除足够的皮肤切缘很重要。本病例报告了一名75岁男性，其右锁骨有一个恶性皮肤病变。磁共振成像显示病变累及肌肉和锁骨。术前活检显示为毛母质瘤特征。对部分锁骨进行了广泛局部切除。动员了斜方肌皮瓣来覆盖缺损。组织病理学和免疫组织化学分析证实为低级别毛母质癌。本病例报告旨在强调毛母质癌可被视为皮肤附属器恶性肿瘤的鉴别诊断之一，并且需要多学科方法来管理此类罕见恶性肿瘤。
