[褐鳟（Salmo trutta，L. 1766）和虹鳟（Salmo gairdneri Richardson，1836）对一种新型弹状病毒感染的反应]

[Response of the brown trout (Salmo trutta, L. 1766) and rainbow trout (Salmo gairdneri Richardson, 1836) to infection by a new rhabdovirus].

作者信息

de Kinkelin P, Baudouy A M, Le Berre M

出版信息

C R Acad Hebd Seances Acad Sci D. 1977 Jan 31;284(5):401-4.

Abstract

Intra peritoneal injection of 200 g Trout hold at + 12 degrees C with 2x10(8) p.f.u. of a new Rhabdovirus (strain 23.75) induces an interferon synthesis within 2 days. (IF titres reaching 2,000 units/ml). 1 month later, the surviving Fish exhibit a specific anti 23.75 neutralizing serum activity (titre 40 to 80) which has been demonstrated to be due to immunoglobulins. This seroneutralization is also recorded in 1/3 of the survivors of natural infection.

摘要

将200克饲养在12摄氏度的鳟鱼腹腔注射2×10⁸ 蚀斑形成单位（p.f.u.）的一种新型弹状病毒（23.75株），会在2天内诱导干扰素合成（干扰素效价达到2000单位/毫升）。1个月后，存活的鱼表现出针对23.75的特异性中和血清活性（效价为40至80），已证明这是由免疫球蛋白引起的。在自然感染的三分之一幸存者中也记录到了这种血清中和现象。