Yamamoto T
Can J Microbiol. 1975 Sep;21(9):1343-7. doi: 10.1139/m75-201.
A total of three hundred and fifty-seven 2-year-old rainbow trout from a hatchery were examined for IPN virus over a period of 5 months. The overall virus isolation rate was 23.2%. The kidneys yielded virus most frequently while the spleen and pancreas-caeca yielded virus less frequently, and the gonads and feces yielded virus infrequently. During this period there was a decline in carrier rate as well as a decline in the numbers of infectious virions in the organs. These decreases were accompanied by elevated levels of neutralizing antibody in the sera. Fish with higher antibody levels were found to lose their IPN carrier status more frequently than those with lower antibody levels.
在5个月的时间里，对来自一家孵化场的总共357条2岁虹鳟鱼进行了传染性胰脏坏死病毒（IPN病毒）检测。总体病毒分离率为23.2%。肾脏最常分离出病毒，脾脏和胰腺盲囊较少分离出病毒，性腺和粪便很少分离出病毒。在此期间，带毒率下降，器官中传染性病毒粒子数量也下降。这些下降伴随着血清中中和抗体水平的升高。发现抗体水平较高的鱼比抗体水平较低的鱼更频繁地失去IPN带毒状态。
