Elinder G, Soback S
Acta Paediatr Scand. 1985 Jul;74(4):574-8. doi: 10.1111/j.1651-2227.1985.tb11032.x.
Primary nocturnal enuresis (PNE) is a very common problem in pediatric and child psychiatric practice. Many treatments have been tried, but none has proved entirely successful. Uristop, a commercially available alarm device based on a theory somewhat different from those used in the common alarm devices, was tried in a prospective randomized double-blind study. Of 134 enuretic children who were examined on an out-patient ward, 53 were selected for inclusion in this study on the basis of certain criteria. The children were randomized either in a treatment group with a functioning device, or in a control group with a non-functioning device. They used their devices for 6 weeks and were followed for an additional 12 weeks. The sex, age, history of previous urinary tract infection (UTI) or treatment of PNE and a family history of PNE were compared between the groups and no statistical differences were found. In the control group, however, there was significantly more often a history of upsetting life events and previous child psychiatric contact. This difference was not considered as having any effect on the results. The results showed that the device had no effect on the study group as compared with the control group. However, both groups improved significantly as compared with the expected sponaneous cessation of bedwetting.
原发性夜间遗尿症（PNE）在儿科和儿童精神病学实践中是一个非常常见的问题。人们尝试了许多治疗方法，但没有一种被证明是完全成功的。Uristop是一种市售的警报装置，其理论与常见警报装置有所不同，在一项前瞻性随机双盲研究中进行了试验。在门诊病房接受检查的134名遗尿儿童中，根据某些标准选择了53名纳入本研究。这些儿童被随机分为使用正常工作装置的治疗组或使用非工作装置的对照组。他们使用装置6周，并额外随访12周。对两组儿童的性别、年龄、既往尿路感染（UTI）病史或PNE治疗史以及PNE家族史进行了比较，未发现统计学差异。然而，在对照组中，生活事件困扰史和既往儿童精神病学接触史更为常见。这种差异被认为对结果没有任何影响。结果表明，与对照组相比，该装置对研究组没有效果。然而，与预期的尿床自然停止相比，两组均有显著改善。
