Mattioni Lorenzo, Nikčević Ana V, Ferri Francesca, Spada Marcantonio M, Sestieri Carlo
Department of Neuroscience, Imaging and Clinical Sciences - and ITAB, Institute for Advanced Biomedical Technologies, G. d'Annunzio University of Chieti-Pescara, Italy.
Department of Psychology, Kingston University, Kingston Upon Thames, UK.
Dialogues Clin Neurosci. 2025 Dec;27(1):34-54. doi: 10.1080/19585969.2025.2481658. Epub 2025 May 23.
People spend most of their waking hours detached from external stimuli, remembering the past, foreseeing the future, imagining situations in which they did not attend or that have never existed, or, simply, thinking. Such a process is crucial for mental health. A common feature of many mental disorders is recurrent stress-related thoughts, the so-called 'perseverative thinking'. In this review, we describe how perseverative thinking represents a dysfunctional self-regulatory strategy that maintains and increases the effects of mental suffering and arises from the maladaptive interplay between discrepancy monitoring, strategy selection, executive regulation, and information representation. We further argue that perseverative thinking can change how the mind represents the world through memory updating, resulting in an increased perceived need for regulation of the external and internal inputs. Lastly, we propose a new integrated model incorporating the different features of perseverative thinking, offering a more unified perspective on psychopathology.
人们在醒着的大部分时间里都与外部刺激脱离,回忆过去、预见未来、想象自己未曾参与或从未存在过的情境,或者仅仅是思考。这样一个过程对心理健康至关重要。许多精神障碍的一个共同特征是反复出现与压力相关的想法,即所谓的“执着性思维”。在这篇综述中,我们描述了执着性思维如何代表一种功能失调的自我调节策略,这种策略维持并加剧了精神痛苦的影响,并且源于差异监测、策略选择、执行调节和信息表征之间的适应不良相互作用。我们进一步认为,执着性思维可以通过记忆更新改变大脑对世界的表征方式,导致对外部和内部输入进行调节的感知需求增加。最后,我们提出了一个新的综合模型,纳入了执着性思维的不同特征,为精神病理学提供了一个更统一的视角。