Myoelectric Activity of the Peroneal Muscles Following Lateral Ankle Sprain: A Cross-Sectional Analysis.

: Lateral ankle sprains can result in adverse outcomes, including reinjuries or chronic ankle instability. The peroneal musculature plays a key role in stabilizing the ankle and preventing sudden ankle inversions that may lead to sprains. : The purpose of the study is to investigate (1) inter-limb differences in peroneal myoelectrical activity in athletes with a history of ankle sprain during the past six months and (2) to investigate peroneal myoelectrical activity differences between athletes with and without a history of ankle sprain. : Sixty-seven athletes (53% females, 46.3% males) were included in this observational cross-sectional study. Self-reported data regarding history of ankle sprain were collected. The peroneal myoelectrical activity was obtained during (1) isometric ankle eversion, (2) dynamic ankle eversions, (3) single leg squat, (4) unilateral and (5) bilateral drop jump test, (6) sprint, and (7) change of direction. : No significant differences in peroneal myoelectrical activity were observed between individuals with (n = 46) and without (n = 21) a history of ankle sprain in the past six months ( > 0.05). Additionally, no significant inter-limb differences were found within the previous ankle sprain group ( > 0.05). : This study found no significant inter-limb differences in peroneal muscle activity among athletes with a history of ankle sprain during the past six months. Moreover, no differences were observed between athletes with and without a history of ankle sprain. This study has certain limitations, including the lack of data regarding the timing and severity of the ankle sprain, as well as the duration and specific characteristics of the rehabilitation process.