University of North Carolina at Chapel Hill.
Datalys Center for Sports Injury Research and Prevention, Indianapolis, IN.
J Athl Train. 2021 Jun 1;56(6):578-585. doi: 10.4085/1062-6050-168-20.
To evaluate the evidence regarding the association between lateral ankle sprain (LAS) history and the subsequent LAS risk, as well as sex differences in the observed associations.
PubMed, CINAHL, and SPORTDiscus were searched through July 2020 for articles on LAS history and incidence during the study period.
Studies were included if they were prospective in nature and the authors reported the number of participants with and those without a history of LAS at study initiation as well as the number of participants in each group who sustained an LAS during the investigation.
Data were study design parameters as well as the number of participants with and those without an LAS history and the number of subsequent LASs that occurred in both groups. Risk ratios (RRs) with 95% CIs compared the risk of LAS during the study period between those with and those without an LAS history for each investigation.
A total of 19 studies involving 6567 patients were included. The follow-up periods ranged from 14 weeks to 2 years. Assessment scores indicated the studies were of moderate to high quality. A significantly higher risk of LAS during the study period was observed among those with a history of LAS in 10 of 15 studies (RR range = 1.29-6.06). Similar associations were seen in 4 of 6 studies of all-male samples (RR range = 1.38-8.65) and 1 of 4 studies with an all-female sample (RR = 4.28).
Strong evidence indicates that a previous LAS increased the risk of a subsequent LAS injury. Men with a history of LAS appeared to be at a higher risk of sustaining a subsequent LAS, but women were not. However, further data are needed to draw definitive conclusions from the limited number of sex-specific studies.
评估既往外侧踝关节扭伤（LAS）病史与随后 LAS 风险之间的关联证据，以及观察到的相关性中的性别差异。
通过 2020 年 7 月在 PubMed、CINAHL 和 SPORTDiscus 上检索关于 LAS 病史和研究期间发病率的文章。
如果研究为前瞻性且作者报告了研究开始时有和无 LAS 病史的参与者数量以及每组中在研究期间发生 LAS 的参与者数量，则纳入研究。
数据为研究设计参数以及有和无 LAS 病史的参与者数量以及两组中随后发生的 LAS 数量。风险比（RR）及其 95%置信区间比较了研究期间有和无 LAS 病史的参与者的 LAS 风险。
共纳入 19 项涉及 6567 名患者的研究。随访期从 14 周至 2 年不等。评估评分表明研究质量为中等到高度。在 15 项研究中有 10 项研究（RR 范围=1.29-6.06）观察到既往 LAS 患者在研究期间发生 LAS 的风险显著更高，在 6 项全部为男性样本的研究中有 4 项研究（RR 范围=1.38-8.65）和 4 项研究中有 1 项研究（RR=4.28）全部为女性样本。
有强有力的证据表明既往 LAS 增加了随后发生 LAS 损伤的风险。有 LAS 病史的男性似乎更有可能发生随后的 LAS，但女性并非如此。然而，由于特定性别研究的数量有限，还需要进一步的数据来得出明确的结论。
