Hall J M, Davis C, Cole R D
FEBS Lett. 1985 Sep 9;189(1):92-6. doi: 10.1016/0014-5793(85)80849-8.
Histone H1(0) is an H1 subfraction whose level on the chromatin is inversely correlated with the mitotic index of the cell. We investigated the increase in H1(0) in 6 cell lines when cell division was blocked by 4 methods: 5 mM butyrate, 2% DMSO, serum withdrawal or density inhibition. The 6 cell lines (HeLa S1 and S3, CHO, 3T6, NIE-115 and Vero) responded differently to the treatments as regards the amount of increase in H1(0) and comparisons among the lines reveal no obvious similarities between the lines in the differential effects of the various treatments on H1(0) levels.
组蛋白H1(0)是一种H1亚组分，其在染色质上的水平与细胞的有丝分裂指数呈负相关。我们通过四种方法阻断细胞分裂，研究了6种细胞系中H1(0)的增加情况：5 mM丁酸盐、2%二甲基亚砜、血清剥夺或密度抑制。这6种细胞系（HeLa S1和S3、CHO、3T6、NIE-115和Vero）对这些处理在H1(0)增加量方面反应不同，各细胞系之间的比较显示，不同处理对H1(0)水平的差异效应在各细胞系之间没有明显相似之处。
