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英国癫痫研究所癫痫性猝死(SUDEP)研讨会:确定SUDEP研究的临床前和临床重点。

Epilepsy Research Institute UK Sudden Unexpected Death in Epilepsy (SUDEP) workshop: Identifying the pre-clinical and clinical priorities for SUDEP research.

作者信息

Pickard Hannah, Ashby Sammy, Sibree David, Elliott Martin, Bhandare Amol, Wykes Rob C, Sen Arjune

机构信息

Epilepsy Research Institute, Churchill House, 35 Red Lion Square, London, UK.

SUDEP Action, UK.

出版信息

Epilepsy Behav. 2025 Oct;171:110473. doi: 10.1016/j.yebeh.2025.110473. Epub 2025 May 22.

Abstract

The Epilepsy Research Institute's Mortality, Morbidity and Risk Theme workshop on Sudden Unexpected Death in Epilepsy (SUDEP) brought together a diverse group of stakeholders, including basic science researchers, clinicians and clinical researchers, charity partners, bereaved individuals and people with epilepsy to identify important gaps in pre-clinical and clinical SUDEP research. Collectively, the SUDEP workshop highlighted recommendations for future research to address several identified gaps and the need to develop infrastructures that utilise data-driven approaches to reduce SUDEP risk. National and global cross-institution collaborations will be fundamental in driving these research efforts forward.

摘要

癫痫研究所关于癫痫性猝死(SUDEP)的死亡率、发病率和风险主题研讨会汇聚了包括基础科学研究人员、临床医生和临床研究人员、慈善合作伙伴、遗属以及癫痫患者在内的不同利益相关者,以确定临床前和临床SUDEP研究中的重要差距。总体而言,SUDEP研讨会强调了针对未来研究的建议,以填补若干已确定的差距,以及开发利用数据驱动方法降低SUDEP风险的基础设施的必要性。国家和全球跨机构合作对于推动这些研究工作至关重要。

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