Guan Mengyao, Han Zhiliang, Liu Na, Zhou Zhou, Qu Xiangyang, Zhang Tao, Chen Shiyan, Wang Huaping
State Key Laboratory of Advanced Fiber Materials, College of Materials Science and Engineering, Donghua University, Shanghai 201620, PR China.
Research Center for Analysis and Measurement, Donghua University, Shanghai 201620, PR China.
Carbohydr Polym. 2025 Aug 15;362:123693. doi: 10.1016/j.carbpol.2025.123693. Epub 2025 May 1.
Hydrogel based electrodes have been applied in the field of bioelectronics, which is of great significance for constructing a robust human-computer interface. However, achieving both reliable conductivity and tissue matching mechanical properties remains challenging. Here, we report a synergistic strategy for constructing a hydrogel electrode for bioelectronic interface with tissue modulus and high conductivity by bacterial cellulose (BC) template induced growth polypyrrole (PPy) electrical percolation network combining a polymethacryloyloxyethyl trimethyl ammonium chloride (PDMC) hydrophilic network. This strategy balances the modulus and conductivity of the bioelectrode, makes up for the adverse effect of the conductive filler on the mechanical properties of the hydrogel, and constructs an effective conductive pathway. The electrical percolation of the hydrogel can be achieved at a low permeability threshold, and the flexibility (E = 288 kPa) of the hydrogel electrode with high conductivity (135.75 S/m) can be obtained. Moreover, the hydrogel electrode has low interface impedance and superior charge storage and injection capability, which allows higher signal-to-noise ratio of recording epidermal electrophysiological signals than that of commercial electrodes. The conductive, flexible and biocompatible hydrogel prepared here provides a new way to construct reliable bioelectronic devices.
水凝胶基电极已应用于生物电子学领域，这对于构建强大的人机接口具有重要意义。然而，要同时实现可靠的导电性和与组织匹配的机械性能仍然具有挑战性。在此，我们报道了一种协同策略，通过细菌纤维素（BC）模板诱导生长聚吡咯（PPy）导电渗流网络与聚甲基丙烯酰氧乙基三甲基氯化铵（PDMC）亲水性网络相结合，构建具有组织模量和高导电性的用于生物电子接口的水凝胶电极。该策略平衡了生物电极的模量和导电性，弥补了导电填料对水凝胶机械性能的不利影响，并构建了有效的导电通路。水凝胶的导电渗流可以在低渗透阈值下实现，并且可以获得具有高导电性（135.75 S/m）的水凝胶电极的柔韧性（E = 288 kPa）。此外，水凝胶电极具有低界面阻抗以及优异的电荷存储和注入能力，这使得记录表皮电生理信号的信噪比高于商业电极。这里制备的导电、柔性且生物相容的水凝胶为构建可靠的生物电子器件提供了一种新方法。
