Suppr超能文献

评估莫桑比克艾滋病毒感染者的艾滋病毒治疗知识水平:一项混合方法研究,以确定“我们是平等的”运动的见解、差距和影响。

Assessing HIV treatment literacy among men living with HIV in Mozambique: a mixed-methods study to identify insights, gaps and impact from the 'Somos Iguais' campaign.

作者信息

Murire Mercy, Hermann Montague, Chissano Marcos, Rodrigrues Micaela, Chongo Yolanda, Hasen Nina, Bouanchaud Paul

机构信息

HIV & TB, Population Services International, Johannesburg, South Africa

HIV & TB, Population Services International, Washington, District of Columbia, USA.

出版信息

BMJ Open. 2025 May 23;15(5):e083040. doi: 10.1136/bmjopen-2023-083040.

Abstract

OBJECTIVES

This study aimed to understand antiretroviral therapy (ART) adherence norms and beliefs among men living with HIV (MLHIV) in Mozambique, gauge the impact of misconceptions and harmful beliefs, evaluate perceived HIV service quality and assess the effectiveness of a behaviour change campaign (Somos Iguais), particularly among men aged 25-34 years.

DESIGN

A mixed-methods, cross-sectional study using quantitative and qualitative approaches.

SETTING

In Mozambique, over two million individuals live with HIV. This study was conducted in Maputo, Nampula and Sofala provinces.

PARTICIPANTS

The study comprised 10 focus group discussions with MLHIV aged 18-35 years and 58 indepth interviews with MLHIV aged 15-35 years across diverse subpopulations. A quantitative cross-sectional survey was completed by 1934 MLHIV aged 25-34 years.

INTERVENTION

Population Services International developed a behaviour change campaign in 2020 aimed at reaching men age 25-34, who often remain undiagnosed or not virally suppressed.

OUTCOME MEASURE

The study explores key aspects of HIV-related norms, behaviours and beliefs among people living with HIV, including high-risk subpopulations. These key aspects include misinformation, service quality gaps, perceived treatment benefits and the impact of the Somos Iguais campaign.

RESULTS

Significantly more MLHIV who were on ART believed that HIV treatment reduces the risk of transmission compared with those who were not on ART (33% and 10%, respectively; p<0.001). Few, however, understood that undetectable viral loads prevent transmission. This lack of understanding is associated with self-stigma and diminished motivation to stay on ART. More than half (54%) of the survey participants agreed that people who are suspected of having HIV lose respect in their community. Surprisingly, our findings did not suggest that provider stigma hampers ART adherence; instead, concerns centred around clinic privacy while obtaining ART. Many MLHIV received HIV education only after diagnosis at the clinic, highlighting a significant community knowledge gap that intensified stigma and hampered treatment. The Somos Iguais behaviour change campaign resonated well with men already on ART, but less so with those not on treatment.

CONCLUSION

While the study highlights a positive trend in HIV treatment literacy among MLHIV, it showed persistent stigmatising attitudes in the wider community. Investments to enhance knowledge and counter misconceptions about HIV treatment, especially among men not reached by the Somos Iguais campaign, are essential in expanding and sustaining the number of MLHIV virally suppressed on ART. Safeguarding patient confidentiality in clinics is imperative to encourage and sustain ART adherence.

摘要

目的

本研究旨在了解莫桑比克艾滋病毒感染者(MLHIV)的抗逆转录病毒疗法(ART)依从性规范和信念,评估误解和有害信念的影响,评估对艾滋病毒服务质量的认知,并评估一项行为改变运动(Somos Iguais)的有效性,特别是在25 - 34岁男性中。

设计

一项采用定量和定性方法的混合方法横断面研究。

背景

在莫桑比克,超过200万人感染了艾滋病毒。本研究在马普托、楠普拉和索法拉省进行。

参与者

该研究包括与18 - 35岁的艾滋病毒感染者进行10次焦点小组讨论,以及对不同亚人群中15 - 35岁的艾滋病毒感染者进行58次深入访谈。1934名25 - 34岁的艾滋病毒感染者完成了一项定量横断面调查。

干预措施

国际人口服务组织在2020年开展了一项行为改变运动,目标是针对25 - 34岁的男性,这些男性往往未被诊断或病毒载量未得到抑制。

结果测量

该研究探讨了艾滋病毒感染者(包括高危亚人群)中与艾滋病毒相关的规范、行为和信念的关键方面。这些关键方面包括错误信息、服务质量差距、感知到的治疗益处以及Somos Iguais运动的影响。

结果

与未接受抗逆转录病毒治疗的艾滋病毒感染者相比,接受抗逆转录病毒治疗的艾滋病毒感染者中,显著更多的人认为艾滋病毒治疗可降低传播风险(分别为33%和10%;p<0.001)。然而,很少有人明白病毒载量检测不到可预防传播。这种认知不足与自我污名化以及坚持抗逆转录病毒治疗的动力减弱有关。超过一半(54%)的调查参与者同意,被怀疑感染艾滋病毒的人在社区中会失去尊重。令人惊讶的是,我们的研究结果并未表明医护人员的污名化会妨碍抗逆转录病毒治疗的依从性;相反,关注点集中在获取抗逆转录病毒治疗时诊所的隐私问题上。许多艾滋病毒感染者仅在诊所诊断后才接受艾滋病毒教育,这凸显了社区中存在严重的知识差距,加剧了污名化并阻碍了治疗。Somos Iguais行为改变运动在已接受抗逆转录病毒治疗的男性中反响良好,但在未接受治疗的男性中效果较差。

结论

虽然该研究突出了艾滋病毒感染者在艾滋病毒治疗知识方面的积极趋势,但它显示出更广泛社区中持续存在的污名化态度。投资加强对艾滋病毒治疗的知识普及并消除误解,特别是在未受Somos Iguais运动影响的男性中,对于扩大和维持接受抗逆转录病毒治疗且病毒载量得到抑制的艾滋病毒感染者数量至关重要。在诊所保护患者隐私对于鼓励和维持抗逆转录病毒治疗的依从性至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/56a0/12104924/6ebd5a57e70a/bmjopen-15-5-g001.jpg

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验