Chow Vanessa Jane, Hossain Akter, Belci Maurizio, Swarna Shyam S
National Spinal Injuries Centre, Stoke Mandeville Hospital, Buckinghamshire NHS Foundation Trust, Aylesbury, UK.
University of Cardiff, Cardiff, Wales, UK.
Spinal Cord Ser Cases. 2025 May 23;11(1):15. doi: 10.1038/s41394-025-00709-x.
A retrospective case series analysing six cases of Charcot spinal arthropathy.
To evaluate the etiology, clinical manifestations (e.g., pain, trunk instability, autonomic dysreflexia, spasticity), latency period before symptom onset, affected spinal regions, and treatment strategies for Charcot spinal arthropathy.
National Spinal Injury Centre, United Kingdom.
Data were collected and analysed from six patients diagnosed with Charcot spinal arthropathy. Variables examined included the etiology, clinical presentations, spinal regions affected, latency period, and outcomes of treatment approaches. Both conservative management and surgical intervention strategies were evaluated.
Patients exhibited common clinical manifestations such as pain, loss of trunk control, autonomic dysreflexia, and spasticity, with varying latency periods before symptom onset. The thoracic spine was the most frequently affected region. Conservative management successfully stabilized symptoms in most cases, while surgical intervention was necessary in instances of severe trunk instability, refractory pain, or deformity impacting mobility.
Conservative management should be the initial treatment approach for Charcot spinal arthropathy. Surgical intervention is reserved for cases with significant clinical progression, such as unresolved pain, mobility restrictions due to trunk deformity, or urgent complications arising from spinal pathology.
一项回顾性病例系列研究,分析6例夏科氏脊柱关节病病例。
评估夏科氏脊柱关节病的病因、临床表现(如疼痛、躯干不稳、自主神经反射异常、痉挛)、症状出现前的潜伏期、受累脊柱区域以及治疗策略。
英国国家脊髓损伤中心。
收集并分析6例诊断为夏科氏脊柱关节病患者的数据。所检查的变量包括病因、临床表现、受累脊柱区域、潜伏期以及治疗方法的结果。对保守治疗和手术干预策略均进行了评估。
患者表现出疼痛、躯干控制丧失、自主神经反射异常和痉挛等常见临床表现,症状出现前的潜伏期各不相同。胸椎是最常受累的区域。在大多数情况下,保守治疗成功稳定了症状,而在严重躯干不稳、顽固性疼痛或影响活动的畸形情况下,则需要进行手术干预。
保守治疗应作为夏科氏脊柱关节病的初始治疗方法。手术干预适用于临床进展显著的病例,如疼痛未缓解、因躯干畸形导致活动受限或脊柱病变引起的紧急并发症。