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干眼疾病的症状学与影响:患者及医生视角

Symptomology and Impact of Dry Eye Disease: A Patient and Physician Perspective.

作者信息

Cheong Noel, Ang Juliana Hiok-Lian, Kaya Cansu, Kumar Ashish, Lam Sean Shao Wei, Tong Louis

机构信息

Department of Ophthalmology, Li Ka Shing Faculty of Medicine, University of Hong Kong, Pokfulam, Hong Kong SAR, China.

Patient Author, Singapore, Singapore.

出版信息

Ophthalmol Ther. 2025 May 24. doi: 10.1007/s40123-025-01166-3.

DOI:10.1007/s40123-025-01166-3
PMID:40411740
Abstract

Dry eye disease (DED) is a common ocular surface disease that results from tear instability, leading to visual disturbance, decreased work productivity, and reduced quality of life. Contributing factors to DED are multifactorial, ranging from air quality to Sjögren's syndrome (primary or secondary), and the associated comorbidities make management particularly challenging. Additionally, knowledge on the natural history of dry eye is lacking, and there is no consensus on the optimal treatment for various DED subtypes and their comorbidities. It is critical that information remains accurate and accessible to patients, caregivers, and physicians. Here, the experiences of a patient with DED are contextualized by an ophthalmologist with a review of the current available literature on DED to establish a groundwork for future research into DED. The patient experience suggests that a clear and accessible information source for patients and caregivers remains an overlooked aspect of holistic care in DED. Symptoms such as watery eyes and refractive changes are often not well understood by patients, and a systems-based approach suggests that patient care would benefit from multidisciplinary collaborations between ophthalmologists, general physicians, and other health professionals in managing this chronic condition. Further advancements in DED research and delivery of care will depend on increasing community engagement on DED diagnosis, comorbidities, and current evidence-based treatment protocols.

摘要

干眼症(DED)是一种常见的眼表疾病,由泪液不稳定引起,导致视觉障碍、工作效率下降和生活质量降低。干眼症的促成因素是多方面的,从空气质量到干燥综合征(原发性或继发性),且相关的合并症使得治疗尤其具有挑战性。此外,缺乏关于干眼症自然病程的知识,对于各种干眼症亚型及其合并症的最佳治疗方法也没有达成共识。确保患者、护理人员和医生能够获取准确信息至关重要。在此,一位眼科医生结合当前关于干眼症的现有文献,对一名干眼症患者的经历进行了背景分析,为未来干眼症研究奠定基础。患者的经历表明,为患者和护理人员提供清晰易懂的信息来源仍是干眼症整体护理中一个被忽视的方面。患者往往对诸如流泪和屈光变化等症状了解不足,基于系统的方法表明,在管理这种慢性病方面,患者护理将受益于眼科医生、全科医生和其他卫生专业人员之间的多学科合作。干眼症研究和护理提供的进一步进展将取决于提高社区对干眼症诊断、合并症和当前循证治疗方案的参与度。

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本文引用的文献

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Conjunctivochalasis.结膜松弛症
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TFOS Lifestyle: Impact of lifestyle challenges on the ocular surface.TFOS 生活方式:生活方式挑战对眼表的影响。
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Optimizing nutrient inputs by balancing spring wheat yield and environmental effects in the Hetao Irrigation District of China.优化春小麦产量与环境效应的平衡,提高河套灌区养分投入效率。
Sci Rep. 2022 Dec 29;12(1):22524. doi: 10.1038/s41598-022-26668-z.
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Current trends in pharmaceutical treatment of dry eye disease: A review.当前治疗干眼疾病的药物治疗趋势:综述。
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