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[鼻腔良性骨膜下骨母细胞瘤。一例病例的组织学和超微结构研究]

[Benign sub-periosteal osteoblastoma of the nasal cavity. histological and ultrastructural study of a case].

作者信息

Ducastelle T, Dehesdin D, Hemet J, Andrieu-Guitrancourt J

出版信息

Ann Pathol. 1985;5(2):131-6.

PMID:4041187
Abstract

A case of periosteal benign osteoblastoma arising in the left nasal cavity is presented. The tumor develops on the surface of the middle turbinate without evidence of bone destruction. It has been locally excised and has not recurred in 3 1/2 years. The histological aspect is identical to that of the other cases of genuine osteoblastoma. The ultrastructure (the first of a periosteal osteoblastoma) is described. The osteoblasts resemble normal osteoblasts with a few exceptions: irregular nuclei, abundance of well-developed rough-surfaced endoplasmic reticulum and numerous fine filaments. The osteocytes and osteoclasts basically resemble their normal counterparts. The final diagnosis of benign osteoblastoma rests at the light microscopy level. The differential diagnosis are reviewed. Distinguishing histologic and ultrastructural characteristics between this tumor and other benign osteoblastic tumors are discussed.

摘要

本文报告一例发生于左侧鼻腔的骨膜性良性成骨细胞瘤。肿瘤位于中鼻甲表面,无骨质破坏迹象。已行局部切除,3年半未复发。组织学表现与其他真性成骨细胞瘤病例相同。描述了其超微结构(首例骨膜性成骨细胞瘤的超微结构)。成骨细胞与正常成骨细胞相似,但有一些例外:核不规则、丰富的发育良好的粗面内质网和大量细丝。骨细胞和破骨细胞基本与其正常对应物相似。良性成骨细胞瘤的最终诊断基于光镜检查。回顾了鉴别诊断。讨论了该肿瘤与其他良性成骨细胞性肿瘤在组织学和超微结构上的鉴别特征。

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