Sheldon W L, Aspillaga M O, Smith P A, Lind T
Br J Obstet Gynaecol. 1985 Sep;92(9):892-8. doi: 10.1111/j.1471-0528.1985.tb03068.x.
Serial changes in serum zinc and magnesium concentrations have been studied before conception, throughout pregnancy and at 12 weeks postpartum in 15 normal healthy women not receiving iron supplementation, 10 women receiving iron supplementation but otherwise having healthy pregnancies and five insulin-dependent diabetics who also received oral iron. Relative to pre-pregnancy values zinc concentrations progressively decreased throughout pregnancy reaching a nadir at 36 weeks gestation followed by an increase; pre-pregnancy values were achieved by 12 weeks postpartum. Magnesium concentrations also decreased throughout pregnancy reaching a nadir at 32 weeks gestation increasing thereafter again with pre-pregnancy values achieved by 12 weeks postpartum. Iron supplementation in non-diabetic and diabetic women had no significant effect upon the changes in serum concentration of either zinc or magnesium. These results suggest that the decrease in the concentrations of both elements is a normal physiological adjustment to pregnancy and that iron supplementation does not influence these changes.
对15名未补充铁剂的正常健康女性、10名补充铁剂但孕期健康的女性以及5名同时接受口服铁剂治疗的胰岛素依赖型糖尿病患者，在受孕前、整个孕期及产后12周研究了血清锌和镁浓度的系列变化。与孕前值相比，锌浓度在整个孕期逐渐降低，在妊娠36周时达到最低点，随后升高；产后12周恢复到孕前值。镁浓度在整个孕期也降低，在妊娠32周时达到最低点，此后再次升高，产后12周恢复到孕前值。非糖尿病和糖尿病女性补充铁剂对血清锌或镁浓度的变化无显著影响。这些结果表明，两种元素浓度的降低是对妊娠的正常生理调节，补充铁剂不影响这些变化。
