Chen Minfeng, Yang Xianling, Yu Xibo, Lei Huihui, Mao Xinjie
Wenzhou medical university eye hospital, Wenzhou, 325000, Zhejiang, China.
BMC Ophthalmol. 2025 May 26;25(1):312. doi: 10.1186/s12886-025-04134-4.
This study compares the influences of orthokeratology (OK) lenses and highly aspherical lenslets (HAL) on axial length (AL) in myopic anisometropia.
Retrospective analysis was performed on 225 individuals with myopic anisometropia who agreed to wear OK lenses, HAL or single-vision spectacles (SP). Subjects with bilateral myopic anisometropia (BMA) were divided into the following groups: SP-BMA, HAL-BMA and OK-BMA. Further, children with unilateral myopic anisometropia (UMA) were divided into the following groups: SP-UMA, UHAL-UMA (unilateral HAL), BHAL-UMA (bilateral HAL) and OK-UMA (unilateral OK lens). Analyzed the difference in the interocular AL elongation in different groups.
For children with BMA, the interocular difference change in the OK-BMA group (0.15 ± 0.19 mm) was greater than that in the SP-BMA (-0.01 ± 0.20 mm) and HAL-BMA (-0.03 ± 0.17 mm) groups, all P < 0.001. For children with UMA, in the non-myopic eyes, the difference in AL elongation in the BHAL-UMA group (0.10 ± 0.14 mm) was less than that in the SP-UMA (0.28 ± 0.22 mm), UHAL-UMA (0.40 ± 0.22 mm) and OK-UMA (0.47 ± 0.24 mm) groups, all P < 0.001. The interocular change in the UHAL-UMA group (0.29 ± 0.36 mm) and OK-UMA group (0.35 ± 0.25 mm) were all higher than that in the SP-UMA (-0.02 ± 0.23 mm) and BHAL-UMA (0.01 ± 0.18 mm) groups, all P < 0.01.
OK lenses can effectively reduce the interocular AL difference for children with unilateral or bilateral myopic anisometropia. However, HAL only decreased the interocular AL difference for children with UMA when wearing unilateral HAL but it did slow down the AL elongation of the non-myopic eyes in children with UMA when wearing bilateral HAL.
本研究比较角膜塑形术(OK)镜片和高非球面微透镜(HAL)对近视性屈光参差患者眼轴长度(AL)的影响。
对225例同意佩戴OK镜片、HAL或单焦点眼镜(SP)的近视性屈光参差患者进行回顾性分析。双眼近视性屈光参差(BMA)患者分为以下几组:SP - BMA组、HAL - BMA组和OK - BMA组。此外,单眼近视性屈光参差(UMA)儿童分为以下几组:SP - UMA组、UHAL - UMA组(单眼HAL)、BHAL - UMA组(双眼HAL)和OK - UMA组(单眼OK镜片)。分析不同组间眼轴长度伸长的差异。
对于BMA儿童,OK - BMA组的眼轴长度差异变化(0.15±0.19mm)大于SP - BMA组(-0.01±0.20mm)和HAL - BMA组(-0.03±0.17mm),P均<0.001。对于UMA儿童,在非近视眼中,BHAL - UMA组的眼轴长度伸长差异(0.10±0.14mm)小于SP - UMA组(0.28±0.22mm)、UHAL - UMA组(0.40±0.22mm)和OK - UMA组(0.47±0.24mm),P均<0.001。UHAL - UMA组(0.29±0.36mm)和OK - UMA组(0.35±0.25mm)的眼轴长度变化均高于SP - UMA组(-0.02±0.23mm)和BHAL - UMA组(0.01±0.18mm),P均<0.01。
OK镜片可有效减小单眼或双眼近视性屈光参差儿童的眼轴长度差异。然而,HAL仅在单眼佩戴HAL时减小了UMA儿童的眼轴长度差异,但在双眼佩戴HAL时减缓了UMA儿童非近视眼的眼轴长度伸长。