Pains Marcos Barbosa, de Melo Nilce Santos, Leite André Ferreira, Mesquita Carla Ruffeil Moreira, de Souza Figueiredo Paulo Tadeu
School of Public Health of the Federal District, Foundation for Education and Research in Health Sciences, Brasília - Distrito Federal, Brazil.
Department of Health of the Federal District, Brasília - Distrito Federal, Brazil.
Sci Rep. 2025 May 25;15(1):18188. doi: 10.1038/s41598-024-84418-9.
The aim of this study was to evaluate dental treatment outcomes and safety in the Intensive Care Unit (ICU). Data collected included the frequency of dental interventions, the incidence of ventilator-associated pneumonia (VAP), patient demographics, length of ICU stay, and mortality. In the statistical analysis, logistic regression models were utilized to explore associations between dental care and patient outcomes, calculating odds ratios for mortality outcomes, with adjustments for potential confounders. More than three interventions were associated with a lower risk of mortality in both crude (p < 0.0001) and adjusted analyses (p < 0.0001), suggesting a protective effect. Patients who received more frequent dental care demonstrated improved survival outcomes. VAP did not significantly increase mortality risk in this cohort (p = 0.3511). Dental procedures were not conclusively linked to a reduction in mortality; however, they were not associated with any important adverse effects, indicating that they are safe for ICU patients. The findings indicate that regular dental treatment in the ICU may be beneficial to patient survival and does not pose additional safety risks. While VAP did not independently predict mortality, receipt of comprehensive dental care was a protective factor.
本研究的目的是评估重症监护病房(ICU)中的牙科治疗效果和安全性。收集的数据包括牙科干预的频率、呼吸机相关性肺炎(VAP)的发生率、患者人口统计学信息、ICU住院时间和死亡率。在统计分析中,使用逻辑回归模型来探索牙科护理与患者预后之间的关联,计算死亡率结局的比值比,并对潜在混杂因素进行调整。在粗分析(p < 0.0001)和调整分析(p < 0.0001)中,超过三次干预均与较低的死亡风险相关,表明存在保护作用。接受更频繁牙科护理的患者生存结局得到改善。在该队列中,VAP并未显著增加死亡风险(p = 0.3511)。牙科治疗与死亡率降低之间没有确凿的联系;然而,它们与任何重要的不良反应均无关联,这表明它们对ICU患者来说是安全的。研究结果表明,在ICU中进行定期牙科治疗可能对患者生存有益,且不会带来额外的安全风险。虽然VAP并不能独立预测死亡率,但接受全面的牙科护理是一个保护因素。