Garcia-Diaz J F, Essig A
Biophys J. 1985 Sep;48(3):519-23. doi: 10.1016/S0006-3495(85)83807-8.
In voltage-clamped epithelia the cell membrane potential transient during a + 10-mV transepithelial pulse conforms to the expected behavior for a series combination of two linear resistance-capacitance (RC) circuits. The evolution of the cell potential is characterized by a single time constant with values of 30-130 ms in frog skin and Necturus gallbladder. These observations have important consequences for the measurement of cell membrane resistance ratios and the interpretation of current-voltage relations.
在电压钳制的上皮组织中,在 +10 mV跨上皮脉冲期间细胞膜电位瞬变符合两个线性电阻 - 电容(RC)电路串联组合的预期行为。细胞电位的变化以单个时间常数为特征,在蛙皮和美西螈胆囊中的值为30 - 130毫秒。这些观察结果对细胞膜电阻比的测量和电流 - 电压关系的解释具有重要意义。