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电压钳制上皮细胞中的电容性瞬变。

Capacitative transients in voltage-clamped epithelia.

作者信息

Garcia-Diaz J F, Essig A

出版信息

Biophys J. 1985 Sep;48(3):519-23. doi: 10.1016/S0006-3495(85)83807-8.

Abstract

In voltage-clamped epithelia the cell membrane potential transient during a + 10-mV transepithelial pulse conforms to the expected behavior for a series combination of two linear resistance-capacitance (RC) circuits. The evolution of the cell potential is characterized by a single time constant with values of 30-130 ms in frog skin and Necturus gallbladder. These observations have important consequences for the measurement of cell membrane resistance ratios and the interpretation of current-voltage relations.

摘要

在电压钳制的上皮组织中,在 +10 mV跨上皮脉冲期间细胞膜电位瞬变符合两个线性电阻 - 电容(RC)电路串联组合的预期行为。细胞电位的变化以单个时间常数为特征,在蛙皮和美西螈胆囊中的值为30 - 130毫秒。这些观察结果对细胞膜电阻比的测量和电流 - 电压关系的解释具有重要意义。

相似文献

1
Capacitative transients in voltage-clamped epithelia.电压钳制上皮细胞中的电容性瞬变。
Biophys J. 1985 Sep;48(3):519-23. doi: 10.1016/S0006-3495(85)83807-8.

本文引用的文献

4
Contribution of junctional conductance to the cellular voltage-divider ratio in frog skins.
Pflugers Arch. 1983 Dec;399(4):336-41. doi: 10.1007/BF00652761.
10
The low-frequency electrical impedance of the isolated frog skin.离体蛙皮的低频电阻抗
Acta Physiol Scand. 1971 Mar;81(3):355-66. doi: 10.1111/j.1748-1716.1971.tb04910.x.

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