Giannas Rafail, Klironomou Louiza, Skafida Evgenia
Internal Medicine, Syros General Hospital, Ermoupolis, GRC.
Nursing, National and Kapodistrian University of Athens, Syros General Hospital, Ermoupolis, GRC.
Cureus. 2025 Apr 24;17(4):e82954. doi: 10.7759/cureus.82954. eCollection 2025 Apr.
Guillain-Barré syndrome (GBS) is a neurological disorder characterized by progressive and symmetric muscle weakness accompanied by the absence or depression of deep tendon reflexes. It is typically associated with a preceding viral infection, such as the Epstein-Barr virus, cytomegalovirus, hepatitis E virus, and Zika virus, or bacterial pathogens like and Recently, rare cases of GBS have been reported following infection with COVID-19, suggesting a potential association between SARS-CoV-2 and GBS. In this report, we present a clinically and diagnostically confirmed case of GBS following COVID-19 reinfection, which supports emerging data on the neurological complications associated with subsequent episodes of infection by the novel coronavirus.
吉兰-巴雷综合征(GBS)是一种神经系统疾病,其特征为进行性对称性肌无力,并伴有深部腱反射减弱或消失。它通常与先前的病毒感染有关,如爱泼斯坦-巴尔病毒、巨细胞病毒、戊型肝炎病毒和寨卡病毒,或细菌病原体,如 和 。最近,有报道称在感染新型冠状病毒肺炎(COVID-19)后出现了罕见的吉兰-巴雷综合征病例,提示严重急性呼吸综合征冠状病毒2(SARS-CoV-2)与吉兰-巴雷综合征之间可能存在关联。在本报告中,我们介绍了一例经临床和诊断确诊的COVID-19再次感染后发生吉兰-巴雷综合征的病例,这支持了有关新型冠状病毒后续感染相关神经并发症的新出现的数据。