Lu Wang, Tang Rui, Jiahui Xiong, Shipeng Zhang, Tao Guo, Hanyua Wang, Feng Xiong, Hui Xie
Clinical Medical College, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Chengdu Institute of Biology, Chinese Academy of Sciences, Chengdu, China.
Front Nutr. 2025 May 9;12:1528771. doi: 10.3389/fnut.2025.1528771. eCollection 2025.
Hearing loss ranks as the third most prevalent disability globally, significantly impacting individuals and society, and imposing a substantial healthcare burden. The World Health Organization reports that over 1.5 billion people worldwide experience hearing loss, with one-third of these cases attributed to preventable factors. Recently, the influence of diet and nutrition on auditory health has garnered increasing attention.
This study systematically reviews and meta-analyzes the protective effects of dietary nutrients on hearing, examining specific nutrients' impact on hearing loss and their potential biological mechanisms.
A comprehensive search of PubMed, Embase, Web of Science, and the Cochrane Library was conducted for relevant studies up to August 2024. Following PRISMA guidelines, the systematic review was registered in PROSPERO. Included were observational studies assessing the relationship between dietary intake and hearing loss.
Thirty-three studies met inclusion criteria: 21 cross-sectional, 10 cohort, and 2 case-control studies. Meta-analysis revealed significant inverse associations between the intake of vitamin B2, β-carotene, carotenoids, β-cryptoxanthin, fat, protein, fiber, and fish, and the risk of hearing loss.
Certain dietary nutrients may protect hearing health. Increasing intake of antioxidants, fiber, protein, and fish rich in unsaturated fatty acids may help preserve auditory function.Keywords: Hearing loss, dietary nutrients, systematic review, meta-analysis, antioxidants.
https://www.crd.york.ac.uk/PROSPERO/view/CRD42024572118, identifier: CRD42024572118.
听力损失是全球第三大常见残疾，对个人和社会有重大影响，并带来沉重的医疗负担。世界卫生组织报告称，全球超过15亿人患有听力损失，其中三分之一的病例归因于可预防因素。最近，饮食和营养对听觉健康的影响日益受到关注。
本研究系统评价并荟萃分析膳食营养素对听力的保护作用，考察特定营养素对听力损失的影响及其潜在生物学机制。
对截至2024年8月的相关研究在PubMed、Embase、Web of Science和Cochrane图书馆进行全面检索。按照PRISMA指南，该系统评价在PROSPERO中进行了注册。纳入的是评估饮食摄入与听力损失之间关系的观察性研究。
33项研究符合纳入标准：21项横断面研究、10项队列研究和2项病例对照研究。荟萃分析显示，维生素B2、β-胡萝卜素、类胡萝卜素、β-隐黄质、脂肪、蛋白质、纤维和鱼类摄入量与听力损失风险之间存在显著负相关。
某些膳食营养素可能保护听力健康。增加抗氧化剂、纤维、蛋白质和富含不饱和脂肪酸的鱼类的摄入量可能有助于维持听觉功能。关键词：听力损失、膳食营养素、系统评价、荟萃分析、抗氧化剂。
https://www.crd.york.ac.uk/PROSPERO/view/CRD42024572118，标识符：CRD42024572118。
