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脊柱和中枢神经系统布鲁氏菌病的影像学:综述

Imaging of spinal and central nervous system brucellosis: a review.

作者信息

Lipka Sebastian, Zawadzki Radosław, Kilicoglu Zeynep Gamze, Zajkowska Joanna, Łebkowska Urszula, Kubas Bożena

机构信息

Department of Radiology, Medical University of Białystok, Poland.

Department of Radiology, VKF American Hospital, Istanbul, Turkey.

出版信息

Pol J Radiol. 2025 Apr 3;90:e161-e169. doi: 10.5114/pjr/200911. eCollection 2025.

DOI:10.5114/pjr/200911
PMID:40416518
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12099199/
Abstract

Brucellosis is a zoonotic disease caused by Gram-negative bacteria of the genus that can be acquired through contact with a contaminated animal or its secretions. The course of the disease can be acute, chronic, or persistent. Axial skeleton and central nervous system (CNS) are among the most common affected locations and may be involved in each of the forms. Due to the varying clinical picture of the disease, diagnosis is made mainly on the basis of laboratory examinations that detect specific IgM and IgG antibodies in blood or other biological material and/or cultures. Imaging methods, especially magnetic resonance imaging, can aid in establishing proper diagnosis, monitoring of the disease and, to some extent, enable differential diagnosis before obtaining the laboratory tests results. The aim of this review is to present imaging features of infection of the spine and CNS and provide the recent advancements in the field.

摘要

布鲁氏菌病是一种由该属革兰氏阴性细菌引起的人畜共患病,可通过接触受污染的动物或其分泌物而感染。该病病程可为急性、慢性或持续性。中轴骨骼和中枢神经系统(CNS)是最常受影响的部位,且每种形式的布鲁氏菌病都可能累及。由于该病临床表现各异,诊断主要基于实验室检查,即在血液或其他生物材料中检测特异性IgM和IgG抗体及/或进行培养。影像学方法,尤其是磁共振成像,有助于做出正确诊断、监测病情,并且在一定程度上能够在获得实验室检查结果之前进行鉴别诊断。本综述旨在介绍脊柱和中枢神经系统感染的影像学特征,并提供该领域的最新进展。

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本文引用的文献

1
Epidemiology and laboratory testing of Brucella spondylitis.布鲁氏菌性脊柱炎的流行病学和实验室检测。
Sci Rep. 2024 Nov 1;14(1):26345. doi: 10.1038/s41598-024-77391-w.
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Differences in Haematological and Imaging Features of Lumbar Spine Fungal and Infections.腰椎真菌性感染与其他感染在血液学和影像学特征上的差异。
Infect Drug Resist. 2024 Oct 10;17:4349-4357. doi: 10.2147/IDR.S478117. eCollection 2024.
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Seronegative brucella meningitis diagnosed by CSF PCR: report on seven cases.CSF-PCR 诊断的血清阴性布鲁氏菌脑膜炎:7 例报告。
BMC Infect Dis. 2024 Oct 14;24(1):1157. doi: 10.1186/s12879-024-10022-x.
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MRI findings and classification of brucella spondylitis: a China multicenter study.MRI 表现与布鲁氏菌性脊柱炎的分型:一项中国多中心研究。
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Differentiation of tuberculous and brucellar spondylitis using conventional MRI-based deep learning algorithms.基于常规 MRI 的深度学习算法鉴别结核性和布鲁菌性脊柱炎。
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Unveiling Neurobrucellosis: A Case Report Emphasizing Early Diagnosis for Better Outcomes.揭示神经型布鲁氏菌病:一例强调早期诊断以获更佳预后的病例报告。
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Incidence and warning signs for complications of human brucellosis: a multi-center observational study from China.人类布鲁氏菌病并发症的发病率及警示标志:一项来自中国的多中心观察性研究
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