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IPACK-内收肌管阻滞联合应用对青少年自体腘绳肌肌腱重建前交叉韧带术后疼痛管理的影响。

Effect of IPACK-Adductor Canal Block Combination on Adolescent Pain Management After Hamstring Autograft Anterior Cruciate Ligament Reconstruction.

作者信息

Sweeney Colleen M, Bomar James D, Edmonds Eric W

机构信息

University of California, San Diego School of Medicine, La Jolla, California, USA.

Rady Children's Hospital, San Diego, California, USA.

出版信息

Orthop J Sports Med. 2025 May 23;13(5):23259671251331145. doi: 10.1177/23259671251331145. eCollection 2025 May.

Abstract

BACKGROUND

There is no pain management standard for anterior cruciate ligament reconstruction (ACLR) or one that addresses posterior capsule pain from hamstring autograft collection. IPACK (Infiltration of local anesthetic between the Popliteal Artery and Capsule of the Knee) is a novel peripheral nerve block designed as an analgesic for the posterior capsule. IPACK use has been beneficial in decreasing reported pain and medications needed for adult total knee arthroplasty; thus, it may be helpful for ACLR.

HYPOTHESIS

We hypothesized that adding IPACK to the adductor canal block (ACB) would decrease pain levels and opioids provided for adolescents who undergo ACLR with hamstring autografts as compared with local infiltration analgesia (LIA) or ACB only.

STUDY DESIGN

Cohort study; Level of evidence, 3.

METHODS

A retrospective chart review was conducted for 153 adolescent patients, aged 10 to 18 years, who underwent ACLR with hamstring autografts at a single hospital over 17 months. The type of regional block was determined by the surgeon's preference, and patients received LIA only, ACB only, or IPACK + ACB. They were compared across these groups to identify the efficacy of each analgesic.

RESULTS

Patients across the entire cohort received a mean of 31.6 ± 12.9 morphine milligram equivalents (MME); the MME did not differ significantly based on regional blocks of LIA only, ACB only, and IPACK + ACB ( = .234). Pain levels in the postanesthesia care unit (PACU) were not significantly different from the first ( = .293), last ( = .845), highest ( = .816), or lowest ( = .235) pain scores. Patients who received both opioids and non-steroidal anti-inflammatory drugs (NSAIDs) received more MME than patients who only received opioids (10.7 ± 7.1 vs 7.8 ± 4) ( = .003) in the PACU but received similar MME overall ( = .38). In the PACU, patients who received opioids + NSAIDs had a higher highest pain score than those who received opioids only (7 ± 2.1 vs 5.5 ± 2.4) ( < .001).

CONCLUSION

Overall, the amount of MME used at this institution was relatively low; however, the use of IPACK + ACB did not decrease opioid usage or pain levels after ACLR as compared with LIA or ACB only for the adolescent population. Use of any regional block was not superior to LIA for MME or reported pain levels. Given that IPACK + ACB did not decrease MME, it is not recommended to add an IPACK block for ACLR in adolescent patients.

摘要

背景

目前尚无前交叉韧带重建(ACLR)的疼痛管理标准,也没有针对腘绳肌自体移植物取材引起的后关节囊疼痛的处理方法。IPACK(腘动脉与膝关节囊间局部麻醉药浸润)是一种新型外周神经阻滞方法,旨在作为后关节囊的镇痛措施。IPACK已被证明有助于减轻成人全膝关节置换术后报告的疼痛和所需的药物剂量;因此,它可能对ACLR有帮助。

假设

我们假设,与单纯局部浸润镇痛(LIA)或单纯股内收肌管阻滞(ACB)相比,在ACB基础上加用IPACK可降低接受腘绳肌自体移植物ACLR的青少年的疼痛程度和阿片类药物用量。

研究设计

队列研究;证据等级,3级。

方法

对153例年龄在10至18岁之间、在一家医院17个月内接受腘绳肌自体移植物ACLR的青少年患者进行回顾性病历审查。区域阻滞类型由外科医生的偏好决定,患者分别接受单纯LIA、单纯ACB或IPACK+ACB。对这些组进行比较,以确定每种镇痛方法的疗效。

结果

整个队列的患者平均接受31.6±12.9毫克吗啡当量(MME);基于单纯LIA、单纯ACB和IPACK+ACB的区域阻滞,MME无显著差异(P=0.234)。麻醉后护理单元(PACU)的疼痛程度与首次(P=0.293)、末次(P=0.845)、最高(P=0.816)或最低(P=0.235)疼痛评分无显著差异。在PACU中,同时接受阿片类药物和非甾体抗炎药(NSAIDs)的患者比仅接受阿片类药物的患者接受更多的MME(10.7±7.1 vs 7.8±4)(P=0.003),但总体接受的MME相似(P=0.38)。在PACU中,接受阿片类药物+NSAIDs的患者的最高疼痛评分高于仅接受阿片类药物的患者(7±2.1 vs 5.5±2.4)(P<0.001)。

结论

总体而言,该机构使用的MME量相对较低;然而,与青少年人群中仅使用LIA或ACB相比,IPACK+ACB在ACLR后并未减少阿片类药物的使用或疼痛程度。对于MME或报告的疼痛程度,使用任何区域阻滞均不优于LIA。鉴于IPACK+ACB并未减少MME,不建议在青少年患者的ACLR中加用IPACK阻滞。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d2f/12102554/6ace40ba2fe6/10.1177_23259671251331145-fig1.jpg

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