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家庭支持、动机与患者对结核病治疗的依从性:来自印度尼西亚的见解

FAMILY SUPPORT, MOTIVATION, AND PATIENT ADHERENCE TO TUBERCULOSIS TREATMENT: INSIGHTS FROM INDONESIA.

作者信息

Dana Nindrea Ricvan, Chiau Ming Long, Rahman Agustian Dede

机构信息

Department of Medicine, Faculty of Medicine, Universitas Negeri Padang, Bukittinggi, Indonesia, 26181.

School of Medical and Life Sciences, Sunway University, Malaysia, 47500.

出版信息

Afr J Infect Dis. 2025 Apr 7;19(2):43-49. doi: 10.21010/Ajidv19i2.5. eCollection 2025.

DOI:10.21010/Ajidv19i2.5
PMID:40417384
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12102674/
Abstract

BACKGROUND

Tuberculosis (TB) remains a significant public health issue globally, with patient adherence to treatment being critical for successful outcomes.This study aimed to investigate the roles of family support and motivation in influencing adherence to TB treatment in Indonesia.

MATERIALS AND METHODS

A cross-sectional study was conducted among patients at four health centers in Padang Municipality, Indonesia, between January and November 2024. A total of 125 respondents diagnosed with drug-sensitive TB and in the second stage of treatment participated. Data were collected through structured interviews using validated questionnaires, assessing family support, motivation, and treatment adherence. Structural Equation Modeling (SEM) was used to analyze the relationships between variables.

RESULTS

The findings revealed significant relationships between family support and motivation (β = 0.931, t-value = 47.016, P<0.001), family support and adherence to TB treatment (β = 0.229, t-value = 2.743, P=0.006), and motivation and adherence to TB treatment (β = 0.775, t-value = 9.334, P<0.001).

CONCLUSION

Family support and motivation play crucial roles in enhancing patient adherence to TB treatment. Strategies to strengthen family involvement and patient motivation should be integrated into TB control programs to improve treatment outcomes. Further research is recommended to explore additional factors influencing adherence in different contexts.

摘要

背景

结核病在全球范围内仍然是一个重大的公共卫生问题,患者坚持治疗对于取得成功的治疗效果至关重要。本研究旨在调查家庭支持和动机在影响印度尼西亚结核病治疗依从性方面的作用。

材料与方法

2024年1月至11月期间,在印度尼西亚巴东市的四个卫生中心对患者进行了一项横断面研究。共有125名被诊断为药敏结核病且处于治疗第二阶段的受访者参与。通过使用经过验证的问卷进行结构化访谈收集数据,评估家庭支持、动机和治疗依从性。采用结构方程模型(SEM)分析变量之间的关系。

结果

研究结果显示家庭支持与动机之间存在显著关系(β = 0.931,t值 = 47.016,P<0.001),家庭支持与结核病治疗依从性之间存在显著关系(β = 0.229,t值 = 2.743,P = 0.006),以及动机与结核病治疗依从性之间存在显著关系(β = 0.775,t值 = 9.334,P<0.001)。

结论

家庭支持和动机在提高患者对结核病治疗的依从性方面发挥着关键作用。应将加强家庭参与和患者动机的策略纳入结核病控制项目,以改善治疗效果。建议进一步开展研究,探索在不同背景下影响依从性的其他因素。

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本文引用的文献

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Jpn J Nurs Sci. 2025 Jan;22(1):e12629. doi: 10.1111/jjns.12629.
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Stigma in Tuberculosis: Time to Act on an Important and Largely Unaddressed Issue.结核病中的耻辱感:是时候应对这个重要且基本未得到解决的问题了。
Cureus. 2024 Jun 8;16(6):e61964. doi: 10.7759/cureus.61964. eCollection 2024 Jun.
3
MODIFIABLE AND NON-MODIFIABLE RISK FACTORS FOR TUBERCULOSIS AMONG ADULTS IN INDONESIA: A SYSTEMATIC REVIEW AND META-ANALYSIS.
印度尼西亚成年人结核病的可改变和不可改变风险因素:一项系统评价与荟萃分析
Afr J Infect Dis. 2024 Mar 8;18(2):19-28. doi: 10.21010/Ajidv18i2.3. eCollection 2024.
4
Management of drug-resistant tuberculosis in Indonesia: a four-year cascade of care analysis.印度尼西亚耐多药结核病的管理:一项为期四年的治疗过程分析
Lancet Reg Health Southeast Asia. 2023 Nov 2;22:100294. doi: 10.1016/j.lansea.2023.100294. eCollection 2024 Mar.
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Knowledge, attitude, and utilization of traditional medicine within the plural medical system in West Java, Indonesia.印度尼西亚西爪哇多元医疗体系中传统医学的知识、态度和应用。
BMC Complement Med Ther. 2024 Jan 30;24(1):64. doi: 10.1186/s12906-024-04368-7.
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Nonadherence to anti-tuberculosis treatment, reasons and associated factors among pulmonary tuberculosis patients in the communities in Indonesia.印度尼西亚社区肺结核患者抗结核治疗不依从、原因及相关因素。
PLoS One. 2023 Aug 8;18(8):e0287628. doi: 10.1371/journal.pone.0287628. eCollection 2023.
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BMC Pulm Med. 2023 Apr 25;23(1):139. doi: 10.1186/s12890-023-02440-5.
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A scoping review of patient-centred tuberculosis care interventions: Gaps and opportunities.以患者为中心的结核病护理干预措施的范围综述:差距与机遇
PLOS Glob Public Health. 2023 Feb 2;3(2):e0001357. doi: 10.1371/journal.pgph.0001357. eCollection 2023.
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