Tinelli Andrea, Mynbaev Ospan, Panese Gaetano, Licchelli Martina, Pecorella Giovanni, Malvasi Antonio, Kosmas Ioannis, Stark Michael, Cao Wenming
Department of Obstetrics and Gynecology and CERICSAL, CEntro di RIcerca Clinico SALentino, Veris Delli Ponti Hospital, Scorrano, Lecce, Italy.
The New European Surgical Academy (NESA), Berlin, Germany.
Front Med (Lausanne). 2025 May 9;12:1564667. doi: 10.3389/fmed.2025.1564667. eCollection 2025.
To define the impact of cervical fibroids (CFs) localization, size, and their combined presence on the feasibility of performing cervical intracapsular myomectomy (CIME) by using a vaginal approach.
Evaluation of the feasibility of conducting CIME via the transvaginal approach.
This retrospective cohort observational study included 32 patients who underwent CIME. The findings were evaluated by comparing them with the outcomes of 1,204 patients with CFs reported in the English and Chinese literature.
The study demonstrated that CIME by vaginal approach can be successfully performed on CFs with a mean size of 8.08 cm (95% CI: 7.44-8.73 cm) for extracervical anterior and posterior sites, 7.61 cm (95% CI: 7.09-8.14 cm) for extracervical and intracervical lateral localizations, and 5.36 cm (95% CI: 4.71-6.35 cm) for combined CFs in two different localization sites. The feasibility and efficiency of the suggested CIME technique were confirmed through a comparative analysis of perioperative endpoints from 326 vaginal, 643 laparoscopic, and 235 laparotomic myomectomies documented in the literature.
The findings highlight key issues related to the suggested original CIME technique performed via a direct vaginal approach. They also provide a comprehensive classification of CFs along with the CFs' clinical manifestations based on the type of growth direction, locations, and fibroid maturity. These findings may have implications for managing patients with CFs.
确定宫颈肌瘤(CFs)的位置、大小及其联合存在情况对经阴道途径行宫颈包膜内肌瘤切除术(CIME)可行性的影响。
评估经阴道途径进行CIME的可行性。
这项回顾性队列观察研究纳入了32例行CIME的患者。通过与英文和中文文献中报道的1204例CFs患者的结果进行比较来评估研究结果。
研究表明,对于宫颈外前后位的CFs,经阴道途径的CIME可成功用于平均大小为8.08 cm(95%CI:7.44 - 8.73 cm)的肌瘤;对于宫颈外和宫颈内侧面的CFs,平均大小为7.61 cm(95%CI:7.09 - 8.14 cm);对于两个不同定位部位的联合CFs,平均大小为5.36 cm(95%CI:4.71 - 6.35 cm)。通过对文献中记录的326例经阴道、643例腹腔镜和235例开腹肌瘤切除术的围手术期终点进行比较分析,证实了所建议的CIME技术的可行性和有效性。
研究结果突出了与经直接阴道途径实施所建议的原始CIME技术相关的关键问题。它们还根据生长方向、位置和肌瘤成熟度对CFs进行了全面分类,并给出了CFs的临床表现。这些发现可能对CFs患者的管理具有启示意义。