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宫颈肌瘤:根据肌瘤起源、生长方向和位置进行分类的经阴道肌瘤包膜内切除术。

Cervical fibroids: the vaginal intracapsular myomectomy with classification by the fibroids' origin, growth directions, and localizations.

作者信息

Tinelli Andrea, Mynbaev Ospan, Panese Gaetano, Licchelli Martina, Pecorella Giovanni, Malvasi Antonio, Kosmas Ioannis, Stark Michael, Cao Wenming

机构信息

Department of Obstetrics and Gynecology and CERICSAL, CEntro di RIcerca Clinico SALentino, Veris Delli Ponti Hospital, Scorrano, Lecce, Italy.

The New European Surgical Academy (NESA), Berlin, Germany.

出版信息

Front Med (Lausanne). 2025 May 9;12:1564667. doi: 10.3389/fmed.2025.1564667. eCollection 2025.

DOI:10.3389/fmed.2025.1564667
PMID:40417667
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12101086/
Abstract

AIM OF THE STUDY

To define the impact of cervical fibroids (CFs) localization, size, and their combined presence on the feasibility of performing cervical intracapsular myomectomy (CIME) by using a vaginal approach.

OBJECTIVE

Evaluation of the feasibility of conducting CIME via the transvaginal approach.

MATERIALS AND METHODS

This retrospective cohort observational study included 32 patients who underwent CIME. The findings were evaluated by comparing them with the outcomes of 1,204 patients with CFs reported in the English and Chinese literature.

RESULTS

The study demonstrated that CIME by vaginal approach can be successfully performed on CFs with a mean size of 8.08 cm (95% CI: 7.44-8.73 cm) for extracervical anterior and posterior sites, 7.61 cm (95% CI: 7.09-8.14 cm) for extracervical and intracervical lateral localizations, and 5.36 cm (95% CI: 4.71-6.35 cm) for combined CFs in two different localization sites. The feasibility and efficiency of the suggested CIME technique were confirmed through a comparative analysis of perioperative endpoints from 326 vaginal, 643 laparoscopic, and 235 laparotomic myomectomies documented in the literature.

CONCLUSION

The findings highlight key issues related to the suggested original CIME technique performed via a direct vaginal approach. They also provide a comprehensive classification of CFs along with the CFs' clinical manifestations based on the type of growth direction, locations, and fibroid maturity. These findings may have implications for managing patients with CFs.

摘要

研究目的

确定宫颈肌瘤(CFs)的位置、大小及其联合存在情况对经阴道途径行宫颈包膜内肌瘤切除术(CIME)可行性的影响。

目的

评估经阴道途径进行CIME的可行性。

材料与方法

这项回顾性队列观察研究纳入了32例行CIME的患者。通过与英文和中文文献中报道的1204例CFs患者的结果进行比较来评估研究结果。

结果

研究表明,对于宫颈外前后位的CFs,经阴道途径的CIME可成功用于平均大小为8.08 cm(95%CI:7.44 - 8.73 cm)的肌瘤;对于宫颈外和宫颈内侧面的CFs,平均大小为7.61 cm(95%CI:7.09 - 8.14 cm);对于两个不同定位部位的联合CFs,平均大小为5.36 cm(95%CI:4.71 - 6.35 cm)。通过对文献中记录的326例经阴道、643例腹腔镜和235例开腹肌瘤切除术的围手术期终点进行比较分析,证实了所建议的CIME技术的可行性和有效性。

结论

研究结果突出了与经直接阴道途径实施所建议的原始CIME技术相关的关键问题。它们还根据生长方向、位置和肌瘤成熟度对CFs进行了全面分类,并给出了CFs的临床表现。这些发现可能对CFs患者的管理具有启示意义。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/59f3/12101086/0407f4eef051/fmed-12-1564667-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/59f3/12101086/ff09eb8f324f/fmed-12-1564667-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/59f3/12101086/56845596350b/fmed-12-1564667-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/59f3/12101086/832a7fdc3722/fmed-12-1564667-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/59f3/12101086/3accce4fbbd9/fmed-12-1564667-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/59f3/12101086/c9597dd99406/fmed-12-1564667-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/59f3/12101086/0407f4eef051/fmed-12-1564667-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/59f3/12101086/ff09eb8f324f/fmed-12-1564667-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/59f3/12101086/56845596350b/fmed-12-1564667-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/59f3/12101086/832a7fdc3722/fmed-12-1564667-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/59f3/12101086/3accce4fbbd9/fmed-12-1564667-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/59f3/12101086/c9597dd99406/fmed-12-1564667-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/59f3/12101086/0407f4eef051/fmed-12-1564667-g006.jpg

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本文引用的文献

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Exploring Surgical Strategies for Uterine Fibroid Treatment: A Comprehensive Review of Literature on Open and Minimally Invasive Approaches.探索子宫肌瘤治疗的手术策略:对开放和微创方法文献的综合回顾。
Medicina (Kaunas). 2023 Dec 28;60(1):64. doi: 10.3390/medicina60010064.
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Large Cervical Leiomyoma of the Uterus: A Rare Cause of Chronic Pelvic Pain Associated With Obstructive Uropathy and Renal Dysfunction: A Case Report.巨大子宫颈平滑肌瘤:慢性盆腔疼痛伴梗阻性尿路病和肾功能不全的罕见病因:一例报告
Cureus. 2023 Jan 5;15(1):e33387. doi: 10.7759/cureus.33387. eCollection 2023 Jan.
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Laparoscopic myomectomy for posterior cervical myoma: authors' experience and strategy.
腹腔镜下宫颈后壁肌瘤切除术:作者的经验与策略
Am J Transl Res. 2022 Dec 15;14(12):9040-9046. eCollection 2022.
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Uterine Artery Embolization and Double-J (DJ) Stenting in a Case of Urinary Retention Due to a Massive Cervical Fibroid: A Case Report.子宫动脉栓塞术联合双J(DJ)支架置入治疗巨大宫颈肌瘤致尿潴留1例:病例报告
Cureus. 2022 Oct 6;14(10):e30013. doi: 10.7759/cureus.30013. eCollection 2022 Oct.
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Tips and Details for Successful Robotic Myomectomy: Single-Center Experience with the First 125 Cases.成功实施机器人子宫肌瘤切除术的技巧与细节:单中心125例首诊病例经验
J Clin Med. 2022 Jun 5;11(11):3221. doi: 10.3390/jcm11113221.
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Strategies and Outcomes of Total Laparoscopic Hysterectomy for Large Uterine Cervical Fibroids.腹腔镜下子宫颈巨大肌瘤全子宫切除术的策略和结局。
JSLS. 2021 Oct-Dec;25(4). doi: 10.4293/JSLS.2021.00031.
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The impact of cervical conization size with subsequent cervical length changes on preterm birth rates in asymptomatic singleton pregnancies.宫颈锥切术大小对无症状单胎妊娠早产率的影响及宫颈长度变化。
Sci Rep. 2021 Oct 5;11(1):19703. doi: 10.1038/s41598-021-99185-0.
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