Suppr超能文献

妇科抗体药物相关临床研究综述:来自ClinicalTrials.gov的见解

Comprehensive overview of antibody drug-related clinical studies in gynecology: insights from ClinicalTrials.gov.

作者信息

Zhou Xiaoling, Xiao Li, Lai Fan, Chen Wei, Zhou Congrong, Deng Yi, Wang Tao, Xing Shasha, Diao Haoyang, Tang Mi, Guo Wenmei, Luo Erdan

机构信息

Department of Pharmacy, Chengdu Women's and Children's Central Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu, China.

Department of Medical Affairs, Chengdu Women's and Children's Central Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu, China.

出版信息

Front Med (Lausanne). 2025 May 9;12:1521587. doi: 10.3389/fmed.2025.1521587. eCollection 2025.

Abstract

Antibodies have been widely used globally over the past decade and play an increasingly important role in modern medicine. Notably, significant advancements have been achieved in the realm of gynecology, particularly in gynecological cancers. This study endeavors to present a thorough overview of antibody-related drug clinical studies in gynecology registered on ClinicalTrials.gov, focusing on the basic characteristics of trials, geographical distribution, administration routes, indications, and targets. The analysis indicates a rising prevalence of antibody-drug conjugates (ADCs), bispecific antibodies, and Fc-fusion proteins. This study will help develop new ideas for future research on antibodies in gynecology.

摘要

在过去十年中,抗体在全球范围内得到了广泛应用,并在现代医学中发挥着越来越重要的作用。值得注意的是,在妇科领域,尤其是妇科癌症方面取得了重大进展。本研究旨在全面概述在ClinicalTrials.gov上注册的妇科抗体相关药物临床研究,重点关注试验的基本特征、地理分布、给药途径、适应症和靶点。分析表明,抗体药物偶联物(ADC)、双特异性抗体和Fc融合蛋白的应用越来越普遍。本研究将有助于为未来妇科抗体研究开拓新思路。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c173/12098050/ebb476871f53/fmed-12-1521587-g001.jpg

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验