Szwedyc Anika, Alaluusua Suvi, Vuola Pia, Pitkänen Veera, Saarikko Anne
Cleft and Craniofacial Center, Helsinki University Hospital, Helsinki, Finland.
J Craniofac Surg. 2025 May 26;36(8):2786-93. doi: 10.1097/SCS.0000000000011465.
The optimal surgical approach for treating velopharyngeal insufficiency (VPI) in patients with cleft is unknown. Hence, the authors reported the outcomes and success rates of the Furlow Z-plasty and pharyngeal flap procedures for treating VPI in all types of clefts. The authors included 377 patients in this study, of whom 351 and 26 underwent Furlow Z-plasty and the pharyngeal flap procedures, respectively. The authors retrospectively assessed the outcomes of both procedures in 3 groups: the nonsyndromic, Robin sequence (RS), and syndromic groups. All patients were evaluated by speech pathologists preoperatively and postoperatively. The success rate of VPI correction after Furlow Z-plasty was 82%; however, 12% required a reoperation for residual VPI. Patients in the syndromic group had significantly higher VPI rates than their nonsyndromic counterparts (P<0.001). The success rate was 81% after the pharyngeal flap procedure; however, 8% of patients required a second operation for residual VPI. The postoperative VPF of patients in the nonsyndromic and RS groups did not significantly differ compared with the syndromic group (P=0.782). Some patients (12%) developed obstructive sleep apnea (OSA) after the pharyngeal flap procedure; however, none developed it after the Furlow Z-plasty. The median hospital length of stay after the pharyngeal flap procedure was prolonged compared with that after the Furlow Z-plasty (P<0.001). Both procedures were effective in correcting VPI. Children in the syndromic group had an increased rate of VPI after Furlow Z-plasty. Development of OSA and prolonged hospital stay were observed after the pharyngeal flap procedure.
治疗腭裂患者腭咽闭合不全(VPI)的最佳手术方法尚不清楚。因此,作者报告了Furlow Z形瓣手术和咽瓣手术治疗各类腭裂患者VPI的结果及成功率。作者将377例患者纳入本研究,其中351例和26例分别接受了Furlow Z形瓣手术和咽瓣手术。作者对非综合征型、罗宾序列征(RS)和综合征型三组患者的两种手术结果进行了回顾性评估。所有患者在术前和术后均由言语病理学家进行评估。Furlow Z形瓣手术后VPI矫正成功率为82%;然而,12%的患者因残留VPI需要再次手术。综合征型组患者的VPI发生率显著高于非综合征型组患者(P<0.001)。咽瓣手术后成功率为81%;然而,8%的患者因残留VPI需要二次手术。非综合征型组和RS组患者术后的VPF与综合征型组相比无显著差异(P=0.782)。一些患者(12%)在咽瓣手术后出现阻塞性睡眠呼吸暂停(OSA);然而,Furlow Z形瓣手术后无一例出现。与Furlow Z形瓣手术后相比,咽瓣手术后的中位住院时间延长(P<0.001)。两种手术在矫正VPI方面均有效。综合征型组儿童在Furlow Z形瓣手术后VPI发生率增加。咽瓣手术后观察到OSA的发生和住院时间延长。