Conti Federica
Madsen Building, School of Physics, University of Sydney, Sydney, NSW, Australia.
Nutr Rev. 2025 May 26. doi: 10.1093/nutrit/nuaf062.
Humans spend approximately one third of their life asleep but, as counterintuitive as it may sound, sleep is far from being a quiet state of inactivity. Sleep provides the opportunity to perform numerous biological and physiological functions that are essential to health and wellbeing, including memory consolidation, physical recovery, immunoregulation, and emotional processing. Yet, sleep deprivation, chronic sleep restriction, and various types of sleep disorders are all too common in modern society. Failure to meet the recommended 7-9 hours of restful sleep per night is known to increase the risk of several health conditions, reason why regular and adequate sleep should be seen as a priority instead of an unnecessary commodity easily traded as required by the commitments of our busy lives. While both the quantity and the quality of sleep can be largely improved with relatively straightforward practices dictated by good sleep hygiene, emerging research suggests that dietary and supplementation protocols focused on certain foods, nutrients, and biochemical compounds with sleep-promoting properties can act as subsidiary sleep aids in complementing these behavioral changes. The scope of this narrative review is to summarize the available evidence on the potential benefits of selected nutraceuticals in the context of circadian rhythm and sleep disturbances, namely melatonin, magnesium, omega-3 fatty acids, tart cherry juice, kiwifruit, apigenin, valerian root, L-theanine, glycine, ashwagandha, myoinositol, Rhodiola rosea, and phosphatidylserine. A comprehensive recapitulation of the relevant literature is provided, alongside corresponding evidence-based nutritional protocols to promote and improve restful sleep.
人类一生中有大约三分之一的时间在睡眠中度过,但听起来可能有违直觉的是,睡眠远非一种安静的静止状态。睡眠为执行众多对健康和幸福至关重要的生物和生理功能提供了机会,包括记忆巩固、身体恢复、免疫调节和情绪处理。然而,睡眠剥夺、长期睡眠限制和各种类型的睡眠障碍在现代社会中极为常见。众所周知,每晚未能达到建议的7至9小时安稳睡眠会增加患多种健康问题的风险,因此,规律且充足的睡眠应被视为优先事项,而非因繁忙生活的各种事务而轻易舍弃的不必要物品。虽然遵循良好的睡眠卫生所规定的相对简单的做法,睡眠的数量和质量在很大程度上都可以得到改善,但新出现的研究表明,专注于某些具有促进睡眠特性的食物、营养素和生化化合物的饮食和补充方案,可以作为辅助睡眠辅助手段,补充这些行为改变。本叙述性综述的范围是总结关于选定的营养保健品在昼夜节律和睡眠障碍背景下潜在益处的现有证据,即褪黑素、镁、ω-3脂肪酸、酸樱桃汁、猕猴桃、芹菜素、缬草根、L-茶氨酸、甘氨酸、南非醉茄、肌醇、红景天和磷脂酰丝氨酸。本文提供了相关文献的全面概述,以及相应的基于证据的营养方案,以促进和改善安稳睡眠。