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穹窿下器中循环血管紧张素II敏感神经元改变大鼠下丘脑室旁核神经垂体神经元活动的电生理证据。

Electrophysiological evidence that circulating angiotensin II sensitive neurons in the subfornical organ alter the activity of hypothalamic paraventricular neurohypophyseal neurons in the rat.

作者信息

Tanaka J, Kaba H, Saito H, Seto K

出版信息

Brain Res. 1985 Sep 9;342(2):361-5. doi: 10.1016/0006-8993(85)91137-0.

DOI:10.1016/0006-8993(85)91137-0
PMID:4041838
Abstract

Thirteen neurons in the subfornical organ (SFO) were antidromically activated by electrical stimulation of the paraventricular nucleus (PVN) in the rat. The activity of these identified SFO neurons was excited by intravenous injection of angiotensin II (AII). Electrical stimulation of the SFO produced orthodromic excitation (40%) and inhibition (40%) of the activity of putative vasopressin (VP)-secreting PVN neurons. These results suggest that circulating AII sensitive SFO neurons with efferent projections to the PVN have both excitatory and inhibitory influences on the activity of putative VP-secreting neurons in the PVN.

摘要

电刺激大鼠室旁核(PVN)可逆向激活穹窿下器(SFO)中的13个神经元。静脉注射血管紧张素II(AII)可兴奋这些已鉴定的SFO神经元的活动。电刺激SFO可对假定的分泌加压素(VP)的PVN神经元活动产生顺向兴奋(40%)和抑制(40%)。这些结果表明,循环中的AII敏感的、向PVN发出传出投射的SFO神经元对PVN中假定的分泌VP的神经元活动具有兴奋和抑制作用。

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1
Electrophysiological evidence that circulating angiotensin II sensitive neurons in the subfornical organ alter the activity of hypothalamic paraventricular neurohypophyseal neurons in the rat.穹窿下器中循环血管紧张素II敏感神经元改变大鼠下丘脑室旁核神经垂体神经元活动的电生理证据。
Brain Res. 1985 Sep 9;342(2):361-5. doi: 10.1016/0006-8993(85)91137-0.
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Lateral hypothalamic area and paraventricular nucleus connections with subfornical organ neurons: an electrophysiological study in the rat.下丘脑外侧区和室旁核与穹窿下器神经元的连接:大鼠的电生理研究
Neurosci Res. 1988 Oct;6(1):45-52. doi: 10.1016/0168-0102(88)90005-3.
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Subfornical organ and hypothalamic paraventricular nucleus connections with median preoptic nucleus neurons: an electrophysiological study in the rat.穹窿下器官和下丘脑室旁核与视前正中核神经元的连接:大鼠的电生理研究
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Efferent pathways from the region of the subfornical organ to hypothalamic paraventricular nucleus: an electrophysiological study in the rat.从穹窿下器区域到下丘脑室旁核的传出通路:大鼠的电生理学研究
Exp Brain Res. 1986;62(3):509-14. doi: 10.1007/BF00236029.
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Involvement of the median preoptic nucleus in the regulation of paraventricular vasopressin neurons by the subfornical organ in the rat.大鼠穹窿下器对室旁加压素神经元调节作用中视前正中核的参与
Exp Brain Res. 1989;76(1):47-54. doi: 10.1007/BF00253622.
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Subfornical organ neurons with efferent projections to the hypothalamic paraventricular nucleus: an electrophysiological study in the rat.具有向下丘脑室旁核传出投射的穹窿下器神经元:大鼠的电生理研究
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The A1 noradrenergic region enhances the responsivity of hypothalamic paraventricular neurohypophyseal neurons to inputs from the subfornical organ in the rat.
Exp Brain Res. 1987;68(3):586-92. doi: 10.1007/BF00249801.
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Lateral hypothalamic area stimulation excites neurons in the region of the subfornical organ with efferent projections to the hypothalamic paraventricular nucleus in the rat.刺激大鼠下丘脑外侧区会兴奋穹窿下器区域的神经元,这些神经元具有投射至下丘脑室旁核的传出纤维。
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The median preoptic nucleus participates in the control of paraventricular vasopressin neurons by the subfornical organ in the rat.视前正中核参与大鼠穹窿下器对室旁核加压素神经元的调控。
Brain Res. 1988 Oct 4;461(2):403-6. doi: 10.1016/0006-8993(88)90277-6.
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Subfornical organ neurons act to enhance the activity of paraventricular vasopressin neurons in response to intravenous angiotensin II.穹窿下器官神经元在对静脉注射血管紧张素II作出反应时,会增强室旁加压素神经元的活性。
Neurosci Res. 1987 Jun;4(5):424-7. doi: 10.1016/0168-0102(87)90008-3.

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