Walker R F, Aloyo V J
Brain Res. 1985 Sep 16;343(1):188-9. doi: 10.1016/0006-8993(85)91177-1.
The purpose of this study was to determine if serotonin (5-HT) is secreted by the pineal gland and also to define the parameters of its secretion. After radiolabelling the endogenous 5-HT pool, individual pineal glands were placed within perifusion chambers and stimulated with norepinephrine (NE). [3H]5-HT was rapidly released within 1 min of stimulation and secretion continued throughout the period of exposure to NE. The findings suggest that 5-HT, in addition to melatonin, is a hormone of the pineal gland.
本研究的目的是确定血清素（5-羟色胺，5-HT）是否由松果体分泌，并确定其分泌参数。对内源性5-HT池进行放射性标记后，将单个松果体置于灌流室中，并用去甲肾上腺素（NE）刺激。[3H]5-HT在刺激后1分钟内迅速释放，并且在暴露于NE的整个期间持续分泌。这些发现表明，5-HT除褪黑素外，也是松果体的一种激素。
