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胆碱能对丘脑背内侧核输入扣带回皮质的调制作用。

Cholinergic modulation of mediodorsal thalamic input into cingulate cortex.

作者信息

Sikes R W, Defrance J F

出版信息

Brain Res. 1985 Oct 21;345(2):327-31. doi: 10.1016/0006-8993(85)91010-8.

DOI:10.1016/0006-8993(85)91010-8
PMID:4041892
Abstract

Field potentials in cingulate cortex (area 24) produced by electrical stimulation of the mediodorsal thalamic nucleus were diminished by iontophoretic ejection of the cholinergic agonist, carbachol. The effect was frequency dependent: field potentials produced by 7.0 Hz stimulation were reduced by 34%. Potentials produced by 0.5 Hz stimulation were not significantly changed. This reduction was blocked by muscarinic but not nicotinic antagonists.

摘要

通过电刺激丘脑背内侧核在扣带回皮质（24区）产生的场电位，因胆碱能激动剂卡巴胆碱的离子电渗法喷射而减弱。这种效应具有频率依赖性：由7.0赫兹刺激产生的场电位降低了34%。由0.5赫兹刺激产生的电位没有显著变化。这种降低被毒蕈碱拮抗剂而非烟碱拮抗剂阻断。

相似文献

1
Cholinergic modulation of mediodorsal thalamic input into cingulate cortex.胆碱能对丘脑背内侧核输入扣带回皮质的调制作用。
Brain Res. 1985 Oct 21;345(2):327-31. doi: 10.1016/0006-8993(85)91010-8.
2
Evidence for cholinergic muscarinic receptors on mediodorsal thalamic projections to the anterior cingulate cortex.关于丘脑背内侧核向前扣带回皮层投射上胆碱能毒蕈碱受体的证据。
Neurosci Lett. 1983 Sep 30;40(2):99-103. doi: 10.1016/0304-3940(83)90286-0.
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Cingulate cortex response to electrical stimulation of the mediodorsal thalamic nucleus.
Exp Neurol. 1985 Aug;89(2):428-41. doi: 10.1016/0014-4886(85)90102-5.
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Muscarinic receptor binding following cholinergic nerve lesions of the cingulate cortex and hippocampus of the rat.大鼠扣带回皮质和海马胆碱能神经损伤后的毒蕈碱受体结合
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Excitatory projection of the rat subicular complex to the cingulate cortex and synaptic integration with thalamic afferents.大鼠海马下托复合体向扣带回皮质的兴奋性投射及与丘脑传入纤维的突触整合。
Brain Res. 1984 May 28;301(1):25-37. doi: 10.1016/0006-8993(84)90399-8.
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Potentiation of local field potentials in the anterior cingulate cortex evoked by the stimulation of the medial thalamic nuclei in rats.刺激大鼠内侧丘脑核所诱发的前扣带回皮质局部场电位增强。
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Opposing influences on behavior mediated by muscarinic and nicotinic receptors in the rat posterior hypothalamic nucleus.毒蕈碱型和烟碱型受体介导的对大鼠下丘脑后核行为的相反影响。
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Cholinergic excitation of GABAergic interneurons in the rat hippocampal slice.大鼠海马切片中GABA能中间神经元的胆碱能兴奋作用
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Carbachol-induced theta-like activity in entorhinal cortex slices.卡巴胆碱诱导的内嗅皮层切片中的θ样活动。
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Short-term facilitation in the anterior cingulate cortex following stimulation of the medial thalamus in the rat.大鼠内侧丘脑刺激后前扣带回皮质的短期易化
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