Kapelushnik Noa, Nemet Malachy, Benjamin Maor, Ben-Simon Guy J, Landau Prat Daphna
Orbital Ophthalmic Plastic & Lacrimal Surgery Institute, Goldschleger Eye Institute, Sheba Medical Center, Tel Hashomer, 52621, Israel.
Faculty of Medicine, Tel Aviv University, Ramat Aviv, Israel.
Sci Rep. 2025 May 26;15(1):18332. doi: 10.1038/s41598-025-03279-y.
Pregnancy induces significant physiological changes in women, impacting various bodily systems. These alterations can influence ocular health and visual function. Ophthalmologists at our center noted an apparent increase in reports of transient binocular visual disturbances among pregnant women presenting to the Ophthalmic Emergency Room (OER), with no ophthalmic findings. This study aims to examine the rate of Transient Visual Disturbances with Normal Ocular Examination (TraViNo) in pregnant vs. non-pregnant women of childbearing age. A cross-sectional study was conducted at Sheba Medical Center, analyzing data from 562 females between 18 and 50 years of age who presented to the OER during January-March 2019. Data retrieved from the participants' medical records included demographics, medical history, symptoms, comprehensive ophthalmological evaluation findings, and final diagnoses recorded at the OER. Included were 562 females (mean age 31.2 ± 9.0 years), among whom 69 (12.0%) were pregnant (mean pregnancy week 25 ± 11). The mean age was similar for both groups (P = 0.2). Presenting symptoms varied between the groups (P < 0.001), with the most common being visual disturbances in the pregnant group (PG) (58%). TraViNo was the final diagnosis in 86 (15%) study women and significantly more common in the PG (48% vs. 11%, respectively, P < 0.001). Most cases (74%) were bilateral. The additional workup included neurologic examinations in 45 (66%) cases, brain/orbital imaging in 28 (33%), and visual field testing in 8 (12%). Obstetric evaluations performed in the PG were normal except for 2 cases of hypertension. TraViNo is more common during pregnancy. Further research is warranted to identify underlying causes and long-term implications.
怀孕会在女性体内引发显著的生理变化，影响身体的各个系统。这些改变会影响眼部健康和视觉功能。我们中心的眼科医生注意到，前来眼科急诊室（OER）就诊且无眼科检查异常的孕妇中，短暂双眼视觉障碍的报告明显增多。本研究旨在调查育龄期孕妇与非孕妇中正常眼部检查下短暂视觉障碍（TraViNo）的发生率。在舍巴医疗中心进行了一项横断面研究，分析了2019年1月至3月期间前来OER就诊的562名18至50岁女性的数据。从参与者的病历中获取的数据包括人口统计学信息、病史、症状、全面的眼科评估结果以及在OER记录的最终诊断。研究对象包括562名女性（平均年龄31.2±9.0岁），其中69名（12.0%）为孕妇（平均孕周25±11周）。两组的平均年龄相似（P = 0.2）。两组的症状表现有所不同（P < 0.001），孕妇组（PG）最常见的症状是视觉障碍（58%）。TraViNo是86名（15%）研究对象的最终诊断，在PG中更为常见（分别为48%和11%，P < 0.001）。大多数病例（74%）为双侧。额外的检查包括45例（66%）进行了神经学检查，28例（33%）进行了脑部/眼眶成像检查，8例（12%）进行了视野测试。PG组除2例高血压外产科评估均正常。TraViNo在孕期更为常见。有必要进一步研究以确定潜在原因和长期影响。
