• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

一名青少年男性的脊柱硬膜外脓肿:一种不寻常的病因及术中超声的作用

Spinal epidural abscess in an adolescent male: an unusual etiology and the role of intraoperative ultrasound.

作者信息

Amin Mohammed, Sidani Khaled, Housheimy Mohamad, Kawtharani Sarah, Hassanieh Joelle, Amine Ali

机构信息

Division of Neurosurgery, Department of Surgery, American University of Beirut Medical Center, Bliss Street, PO Box 11-0236, Beirut, Lebanon.

出版信息

Childs Nerv Syst. 2025 May 26;41(1):189. doi: 10.1007/s00381-025-06848-8.

DOI:10.1007/s00381-025-06848-8
PMID:40419701
Abstract

BACKGROUND

Pediatric spinal epidural abscess is considered to be a rare illness. Despite all the recent improvements in the diagnosis and the treatment of this rare condition, the morbidity and mortality rate is still high especially if the diagnosis was not achieved early on.

PURPOSE

The purpose of this paper is to review the current literature on spinal epidural abscess (SEA) in the pediatric population, with a focus on understanding the clinical presentation, diagnosis, management strategies, and outcomes. This review aims to highlight the unique aspects of SEA and underscore the role of imaging, including intraoperative ultrasound, in guiding treatment.

METHODS

A literature review was conducted to analyze the existing research on SEA in the pediatric population from the year 2000 to the present. Patients with tuberculosis and predisposing factors were excluded from the analysis.

RESULTS

We found 42 cases of SEA in patients without significant predisposing factors. The most commonly reported symptoms were back pain, fever, and neurological deficits. Early surgical decompression coupled with targeted antibiotic therapy resulted in improved neurological outcomes and reduced morbidity.

CONCLUSION

Current literature reveals no clear consensus on the optimal management of (SEA). Each treatment modality presents distinct considerations. However, a trend favoring surgical management is apparent in the reviewed literature, likely due to the risk of disease progression associated with medical management alone. MRI remains the gold standard for diagnosis, but intraoperative ultrasound may offer added benefits during surgical management.

摘要

背景

小儿脊柱硬膜外脓肿被认为是一种罕见疾病。尽管近年来在这种罕见病症的诊断和治疗方面有了诸多进展,但发病率和死亡率仍然很高,尤其是在早期未确诊的情况下。

目的

本文旨在回顾有关小儿人群脊柱硬膜外脓肿(SEA)的当前文献,重点是了解临床表现、诊断、管理策略和治疗结果。本综述旨在突出SEA的独特方面,并强调影像学(包括术中超声)在指导治疗中的作用。

方法

进行了一项文献综述,以分析2000年至今有关小儿人群SEA的现有研究。分析中排除了患有结核病和有易感因素的患者。

结果

我们发现42例无明显易感因素的SEA患者。最常报告的症状是背痛、发热和神经功能缺损。早期手术减压联合靶向抗生素治疗可改善神经功能结果并降低发病率。

结论

当前文献显示,关于SEA的最佳管理尚无明确共识。每种治疗方式都有不同的考虑因素。然而,在所审查的文献中,倾向于手术管理的趋势很明显,这可能是由于仅采用药物治疗存在疾病进展的风险。MRI仍然是诊断的金标准,但术中超声在手术管理期间可能会提供额外的益处。

相似文献

1
Spinal epidural abscess in an adolescent male: an unusual etiology and the role of intraoperative ultrasound.一名青少年男性的脊柱硬膜外脓肿:一种不寻常的病因及术中超声的作用
Childs Nerv Syst. 2025 May 26;41(1):189. doi: 10.1007/s00381-025-06848-8.
2
Treatment strategies and outcome in patients with non-tuberculous spinal epidural abscess--a review of 46 cases.非结核性脊柱硬膜外脓肿患者的治疗策略与预后——46例病例回顾
Minim Invasive Neurosurg. 2008 Feb;51(1):36-42. doi: 10.1055/s-2007-1004547.
3
Spinal Epidural Abscess in Children: Case Report and Review of the Literature.儿童脊柱硬膜外脓肿:病例报告及文献综述
World Neurosurg. 2019 Jun;126:453-460. doi: 10.1016/j.wneu.2019.01.294. Epub 2019 Feb 22.
4
Spinal epidural abscess: prognostic factors and comparison of different surgical treatment strategies.脊柱硬膜外脓肿:预后因素及不同手术治疗策略的比较
Acta Neurochir (Wien). 2005 Feb;147(2):159-66; discussion 166. doi: 10.1007/s00701-004-0414-1.
5
Extended cervicolumbar spinal epidural abscess associated with paraparesis successfully decompressed using a minimally invasive technique.采用微创技术成功减压与轻瘫相关的颈胸段脊柱硬膜外脓肿。
Spine (Phila Pa 1976). 2004 Jul 15;29(14):E300-3. doi: 10.1097/01.brs.0000131215.46119.dd.
6
Medical and surgical management of spinal epidural abscess: a systematic review.脊柱硬膜外脓肿的医学与外科治疗:一项系统综述
Neurosurg Focus. 2014 Aug;37(2):E4. doi: 10.3171/2014.6.FOCUS14127.
7
Spontaneous spinal epidural abscess in pregnancy: a case series.妊娠自发性脊柱硬膜外脓肿:病例系列。
Spinal Cord Ser Cases. 2021 Aug 26;7(1):79. doi: 10.1038/s41394-021-00437-y.
8
Independent predictors of failure of nonoperative management of spinal epidural abscesses.脊柱硬膜外脓肿非手术治疗失败的独立预测因素。
Spine J. 2014 Aug 1;14(8):1673-9. doi: 10.1016/j.spinee.2013.10.011. Epub 2013 Oct 30.
9
Update on spinal epidural abscess.脊髓硬膜外脓肿的最新进展。
Curr Opin Infect Dis. 2019 Jun;32(3):265-271. doi: 10.1097/QCO.0000000000000544.
10
The indications and timing for operative management of spinal epidural abscess: literature review and treatment algorithm.脊柱硬膜外脓肿的手术治疗指征及时机:文献综述与治疗方案
Neurosurg Focus. 2014 Aug;37(2):E8. doi: 10.3171/2014.6.FOCUS14261.

本文引用的文献

1
Lumbar spine epidural abscess and facet joint septic arthritis in a pediatric patient.一名儿科患者的腰椎硬膜外脓肿和小关节化脓性关节炎。
Pediatr Neonatol. 2023 Jul;64(4):474-475. doi: 10.1016/j.pedneo.2022.12.008. Epub 2023 Jan 26.
2
Large Spinal Abscess in a Neonate.新生儿巨大脊柱脓肿
Neurol India. 2020 Nov-Dec;68(6):1456-1458. doi: 10.4103/0028-3886.304112.
3
Case 3: Fever and Back Pain in an 8-year-old Boy.病例3:一名8岁男孩的发热与背痛
Pediatr Rev. 2020 Apr;41(4):203-205. doi: 10.1542/pir.PIR-2018-0086.
4
Spinal holocord epidural abscess evacuated with double thoracic interval laminectomy: a rare case report with literature review.经双侧胸段椎板间隙切除术引流的脊髓全段硬膜外脓肿:1例罕见病例报告并文献复习
Spinal Cord Ser Cases. 2019 Jul 2;5:62. doi: 10.1038/s41394-019-0206-8. eCollection 2019.
5
Spinal Epidural Abscess in Children: Case Report and Review of the Literature.儿童脊柱硬膜外脓肿:病例报告及文献综述
World Neurosurg. 2019 Jun;126:453-460. doi: 10.1016/j.wneu.2019.01.294. Epub 2019 Feb 22.
6
Beware: Opisthotonic posturing and epidural disease.注意:角弓反张姿势与硬膜外疾病。
J Paediatr Child Health. 2019 Sep;55(9):1133-1135. doi: 10.1111/jpc.14400. Epub 2019 Feb 21.
7
Review and case report demonstrate that spontaneous spinal epidural abscesses are rare but dangerous in childhood.文献回顾和病例报告表明,儿童自发性脊髓硬膜外脓肿虽然罕见,但很危险。
Acta Paediatr. 2019 Jan;108(1):28-36. doi: 10.1111/apa.14579. Epub 2018 Oct 15.
8
Bone and Joint Infections.骨与关节感染
Pediatr Infect Dis J. 2017 Aug;36(8):788-799. doi: 10.1097/INF.0000000000001635.
9
Case 2: Fever and Back Pain in 13-year-old Girl.病例2:一名13岁女孩的发热与背痛
Pediatr Rev. 2017 Jan;38(1):46-47. doi: 10.1542/pir.2014-0127.
10
Rapidly Progressive Spontaneous Spinal Epidural Abscess.快速进展性自发性脊柱硬膜外脓肿
Case Rep Infect Dis. 2016;2016:7958291. doi: 10.1155/2016/7958291. Epub 2016 Sep 5.