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桥脑小出血所致的向上扭转性眼球震颤:一例报告

Upbeat-torsional nystagmus due to a small pontine hemorrhage: A case report.

作者信息

Kimura Mayuka, Fujita Hiroaki, Onuma Hiroki, Suzuki Keisuke

机构信息

Department of Neurology, Dokkyo Medical University, Tochigi, Japan.

出版信息

Medicine (Baltimore). 2025 May 23;104(21):e42064. doi: 10.1097/MD.0000000000042064.

Abstract

RATIONALE

Characteristic nystagmus often predicts a responsible lesion and aids in the differential diagnosis of dizziness or vertigo. Upbeat-torsional nystagmus usually presents with posterior canal benign paroxysmal positional vertigo, which occurs after a few seconds of latency following a change in head position. However, it can also be observed in patients with central lesions. This case report aims to highlight the importance of neurologically examining characteristic nystagmus in detecting central lesions.

PATIENT CONCERNS

A 56-year-old woman suddenly developed dizziness. Neurological examinations revealed torsional nystagmus with a mild upbeat component that was not triggered by head position changes. No other neurological manifestations were present.

DIAGNOSIS

Brain magnetic resonance imaging revealed a left dorsal pontine hemorrhage.

INTERVENTIONS

The patient received antihypertensive treatment. Adenosine triphosphate disodium hydrate was administered as a symptomatic treatment for the patient's dizziness.

OUTCOMES

The torsional nystagmus gradually decreased in frequency and resolved around the 4th day of hospitalization. The patient was able to walk steadily and was discharged home on the 14th day of hospitalization.

LESSONS

Although dizziness with torsional nystagmus is known to be observed in patients with posterior canal benign paroxysmal positional vertigo, when it is sudden, persistent, and occurs independent of head repositioning, central lesions should be considered. Stroke in the brainstem should be considered first, especially in patients with vascular risk factors.

摘要

理论依据

特征性眼球震颤通常可预测责任病灶,并有助于头晕或眩晕的鉴别诊断。上跳扭转性眼球震颤通常表现为后半规管良性阵发性位置性眩晕,在头部位置改变后几秒的潜伏期后出现。然而,在中枢性病变患者中也可观察到。本病例报告旨在强调在检测中枢性病变时对特征性眼球震颤进行神经学检查的重要性。

患者情况

一名56岁女性突然出现头晕。神经学检查发现有扭转性眼球震颤,伴有轻度上跳成分,且不受头部位置变化触发。无其他神经学表现。

诊断

脑部磁共振成像显示左侧脑桥背侧出血。

干预措施

患者接受了降压治疗。给予三磷酸腺苷二钠水合物作为对患者头晕的对症治疗。

结果

扭转性眼球震颤的频率逐渐降低,在住院第4天左右消失。患者能够稳步行走,并于住院第14天出院回家。

经验教训

虽然已知后半规管良性阵发性位置性眩晕患者会出现伴有扭转性眼球震颤的头晕,但当头晕突然、持续且与头部重新定位无关时,应考虑中枢性病变。应首先考虑脑干卒中,尤其是有血管危险因素的患者。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b0da/12113958/e34ae4675645/medi-104-e42064-g001.jpg

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