Canlı Kübra, Demirkıran Gökhan, Can Filiz
Department of Physiotherapy and Rehabilitation, Faculty of Health Sciences, Karadeniz Technical University, Trabzon, Türkiye.
Department of Orthopaedics and Traumatology, Faculty of Medicine, Hacettepe University, Ankara, Türkiye.
BMC Musculoskelet Disord. 2025 May 27;26(1):519. doi: 10.1186/s12891-025-08755-0.
Tactile discrimination training (TDT) and oculomotor exercises (OEs) have been widely used somatosensory-based interventions for a wide range of chronic pain conditions. There is, however, little evidence for the effectiveness of these approaches in people with chronic neck pain. This study aimed to determine the superiority of one intervention over another on pain outcomes in people with chronic neck pain.
Fifty seven participants were randomly divided into three groups: TDT, OEs, and a control group who received no intervention. TDT, OEs groups received either TDT or OEs, respectively, three times per week for four weeks. The control group received no intervention. Pain intensity, neck pain-related disability, pressure pain thresholds (PPTs), mechanical pain of temporal summation (mTSP), and conditioned pain modulation were assessed as pain outcomes. Depending on the normality, a repeated measures ANOVA or F1-LD-F1 design was used to analyse the data.
A significant group*time interaction and main effects for time were found for pain intensity (p: 0.001, p: 0.001, respectively) and pain-related disability (p < 0.019, p < 0.009; respectively). There was a significant main effect for time for mTSP at the painful side of the neck (p: 0.022). TDT and OEs resulted in a significantly higher improvement in pain intensity (p: 0.005, p < 0.001; respectively) and neck pain-related disability (p: 0.005, p: 0.007; respectively). There was a higher improvement in pain intensity in OEs group compared to TDT group (p: 0.010). A significantly higher improvement in PPT at the painful site after OEs was found (p: 0.038). The control group demonstrated a significantly higher improvement in mTSP in the painful area of the neck (p: 0.048). There were no other significant within- or between-group changes.
OEs and TDT are effective somatosensory-based interventions for improving pain intensity and pain-related disability.
This study demonstrated that sensory retraining interventions improves the subjective pain perception.
Trial Registration Number: NCT05605132, Date of trial registration: 10/29/2022, Name of trial registry: Neck Pain.
触觉辨别训练（TDT）和动眼神经训练（OEs）已被广泛用作针对多种慢性疼痛状况的基于体感的干预措施。然而，几乎没有证据表明这些方法对慢性颈部疼痛患者有效。本研究旨在确定在慢性颈部疼痛患者中，一种干预措施相对于另一种干预措施在疼痛结果方面的优越性。
57名参与者被随机分为三组：TDT组、OEs组和未接受干预的对照组。TDT组和OEs组分别每周接受三次TDT或OEs训练，持续四周。对照组不接受干预。评估疼痛强度、颈部疼痛相关残疾、压痛阈值（PPTs）、时间总和的机械性疼痛（mTSP）和条件性疼痛调制作为疼痛结果。根据数据的正态性，使用重复测量方差分析或F1-LD-F1设计来分析数据。
在疼痛强度（p值分别为0.001、0.001）和疼痛相关残疾（p值分别<0.019、<0.009）方面，发现了显著的组×时间交互作用和时间主效应。在颈部疼痛侧的mTSP方面，时间有显著主效应（p值为0.022）。TDT和OEs在疼痛强度（p值分别为0.005、<0.001）和颈部疼痛相关残疾（p值分别为0.005、0.007）方面均导致显著更高的改善。与TDT组相比，OEs组在疼痛强度方面有更高的改善（p值为0.010）。发现OEs后疼痛部位的PPT有显著更高的改善（p值为0.038）。对照组在颈部疼痛区域的mTSP方面有显著更高的改善（p值为0.048）。组内或组间没有其他显著变化。
OEs和TDT是改善疼痛强度和疼痛相关残疾的有效的基于体感的干预措施。
本研究表明感觉再训练干预可改善主观疼痛感知。
试验注册号：NCT05605132，试验注册日期：2022年10月29日，试验注册机构名称：颈部疼痛。
