Asafa Muritala A, Ahmed Ibrahim O, Agim Mary B, Fabinu Taofik A, Kusoro Simeon O, Ogunoye Blessing T, Ogunlade Oluwadare, Bolarinwa Rahman A
Department of Physiological Sciences, Faculty of Basic Medical Sciences, College of Health Sciences, Obafemi Awolowo University, Ile-Ife, Nigeria.
Department of Haematology and Blood Transfusion, Obafemi Awolowo University Teaching Hospitals Complex, Ile-Ife, Nigeria.
BMC Res Notes. 2025 May 26;18(1):233. doi: 10.1186/s13104-025-07303-2.
Reference intervals (RIs) are crucial for the interpretation of results and overall patient management. There are currently no known established reference values for haematological parameters for patients with sickle cell anaemia (SCA) in Nigeria, making it difficult for clinicians to interpret and diagnose abnormalities appropriately. This study aimed at establishing RIs of some haematological indices for individuals with SCA.
Generally, the reference interval for Haematocrit (%) is 17.8 to 29.7, while the WBC (x 10/l) ranged between 5.9 and 12.1 and the platelet count (x 10/l) is 166-465. For the male participants, the reference interval for haematocrit (%) was found to be between 17.8 and 29, the WBC (x 10/l) ranged between 6.7 and 12.1 and the platelet count (x 10/l) was between 166 and 399. The female subjects had a haematocrit (%) of between 18.7 and 28.5, WBC of between 5.9 10/l and 13.0 × 10/l and the platelet count (x 10/l) was between 225 and 465.
参考区间对于结果解读和患者整体管理至关重要。目前在尼日利亚，镰状细胞贫血（SCA）患者血液学参数尚无既定的参考值，这使得临床医生难以恰当地解读和诊断异常情况。本研究旨在确定SCA患者某些血液学指标的参考区间。
一般来说，血细胞比容（%）的参考区间为17.8至29.7，白细胞（×10⁹/L）在5.9至12.1之间，血小板计数（×10⁹/L）为166 - 465。对于男性参与者，血细胞比容（%）的参考区间为17.8至29，白细胞（×10⁹/L）在6.7至12.1之间，血小板计数（×10⁹/L）在166至399之间。女性受试者的血细胞比容（%）在18.7至28.5之间，白细胞在5.9×10⁹/L至13.0×10⁹/L之间，血小板计数（×10⁹/L）在225至465之间。
