非致死性狂犬病感染的早期事件。
Early events in non-lethal rabies infection.
作者信息
Sodja I
出版信息
Acta Virol. 1979 Jul;23(4):335-40.
PMID:40421
Abstract
Inoculation of sublethal doses of rabies virus strains isolated from small wild rodents resulted in non-lethal infection of white mice. During the first 48 hr after inoculation the virus neutralizing and protection activities in mouse sera and brain suspensions increased, followed by a transient decrease on the 3rd and 4th day. In some cases there also occurred transient multiplication of virus, which retained a relatively high infectivity for mice.
摘要
接种从野生小型啮齿动物分离出的亚致死剂量狂犬病病毒毒株，会导致小白鼠发生非致死性感染。接种后的头48小时内，小鼠血清和脑悬液中的病毒中和及保护活性增强，随后在第3天和第4天出现短暂下降。在某些情况下，还会出现病毒的短暂增殖，这种病毒对小鼠仍保持相对较高的感染性。
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